analgesic role of premative Oral Melatonin before thoracic epidural in bilateral multiple fracture ribs

Not Applicable

• Conditions: Injury, Occupational Diseases, Poisoning; pain in patients with bilateral multiple fracture ribs

• Registration Number: PACTR201711002741378
• Lead Sponsor: tana university hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-11-02
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

80 ASA Physical status I &II, 18-50 years presented with bilateral fracture ribs.

Exclusion Criteria

¿Schizophrenia or other psychotic disorder or cognitive impairment
¿ History of drug dependency or substance addiction
¿ A known sensitivity to melatonin or pregabalin,
¿ known to be allergic to any medicines
¿History of drug or alcohol abuse, taking opioids or sedative medications, and had a history of psychiatric conditions.
¿Patients with a history of taking pregabalin or gabapentin
¿pathological rib fractures, kyphoscoliosis
¿BMI <18.5 or >30 kg m2
¿history of cerebro-vascular disease, seizure disorders, central nervous system diseases
¿coagulation disorders
¿local skin infection at the side of injection

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
the time for the first request for rescue analgesia

Secondary Outcome Measures

Name	Time	Method
the severity of pain