Effect of Brazil Nut consumption on mineral Selenium compounds in the continuous use of cholesterol-lowering drugs

Not Applicable

• Conditions: utritional alterations, mineral deficiency; SP6.016.052.068

• Registration Number: RBR-7rwgzt
• Lead Sponsor: Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-08-07
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Adults subjects of both sexes; in chronic use of Statins; with muscle disorders in the case of individuals in the study group; no muscle disorders in the case of individuals in control group

Exclusion Criteria

Presence of serious cardiac complications or other diseases such as thyroid; hematological; congenital; autoimmune; liver disease; renal failure; cancer; associated infections; osteoporosis; postoperative; antibiotics and vitamin and mineral supplements; food allergy to oilseed; current alcoholism and smoking

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Increase in the gene expression of selenoproteins by means of the real-time polymerase chain reaction method, based on the observation of a variation of at least 15% in the measurements before and after supplementation with brazil nuts

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are not expected