Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity

Not Applicable

Completed

• Conditions: Obesity; Exercise; Metabolic Disease
• Interventions: Dietary Supplement: Beetroot Juice; Dietary Supplement: Beetroot Juice no Nitrate; Dietary Supplement: Sodium Nitrate

• Registration Number: NCT03545009
• Lead Sponsor: University of Alabama at Birmingham

Brief Summary

The purpose of this study is to assess the effects of acute beetroot juice supplementation on exercise performance and cardiometabolic health in obese individuals with secondary cardiometabolic complications. Additionally, we will determine if the ergogenic health benefits of beetroot juice is due to the nitric oxide compound within the product, the antioxidant compound within the product, or a combination of the two compounds.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-05-22
• Study First Submitted QC: 2018-05-22
• Study First Posted: 2018-06-04
• Study Start: 2018-08-10
• Primary Completion: 2020-08-30
• Study Completion: 2020-08-30
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-20
• Last Update Posted: 2021-09-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• BMI ≥ 30 kg/m2
• Able to perform exercise testing on a cycle ergometer

Exclusion Criteria

• Currently taking medications know to affect cardiovascular or respiratory function
• Currently supplementing with an antioxidant compound
• Current smoker
• Currently taking antibiotics
• Not willing to abstain from mouthwash use
• Currently participating in regular physical activity

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Beetroot Juice	Beetroot Juice	-
Beetroot Juice no Nitrate	Beetroot Juice no Nitrate	-
Sodium Nitrate	Sodium Nitrate	-

Primary Outcome Measures

Name	Time	Method
Time to Exhaustion	A Time to Exhaustion Test will be conducted on each participant a total of four times throughout their participation in the study. This will take place approximately 2.5 hours post ingestion of the dietary supplement they are randomized to at each visit.

Trial Locations

Locations (1)

University of Alabama at Birmingham; 🇺🇸 Birmingham, Alabama, United States