Response Surface Modeling Between Remimazolam and Sevoflurane: Minto and Greco Model Comparison.
- Conditions
- Diseases of the digestive system
- Registration Number
- KCT0009423
- Lead Sponsor
- Pusan National University Yangsan Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 30
Subjects (15 males, 15 females) scheduled to undergo surgery under general anesthesia in the central operating room at our institute.
Subjects in the American Society of Anesthesiologists physical status classification 1 or 2
Subjects who voluntarily agreed in writing to participate in this study
Subjects who are allergic to remimazolam or sevoflurane.
Subjects without renal, hepatic, neuromuscular, or neurologic disease and taking medications related to these Subjects who are habitually taking psychoactive drugs or have ischemic heart disease.
Pregnant women
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Relationship between sevoflurane and remimazolam (synergistic, additive, infra-additive)
- Secondary Outcome Measures
Name Time Method BIS values for each drug's Ce combination