Effect of House Cricket Preload on Glycemic Response in Type 2 Diabetes Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Blood glucose
研究概览
简要总结
The goal of this trial is to test the effect of house cricket (Acheta domesticus) preload on glycemic response in diabetic patients. The main question[s] it aims to answer are: whether house cricket powder could lower blood glucose spike and stimulate higher insulin response. Participants will consume either house cricket powder, whey protein isolate or placebo which will be mixed with a chicken-flavored soup. Participants fingers will be pricked for up to 2 hours.
Researcher will compare house cricket powder with placebo to see if the glycemic response is better in house cricket supplemented group.
Researcher will compare house cricket powder with whey protein isolate to see if both supplement induce comparable glycemic response.
详细描述
Participants blood will be collected at 8 time points:
Baseline 20 minutes after pre load 15 minutes after Oral Glucose Tolerance Test (OGTT) 30 minutes after OGTT 45 minutes after OGTT 60 minutes after OGTT 90 minutes after OGTT 120 minutes after OGTT
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Suffering from type 2 diabetes mellitus (HbA1c > 6.5%)
- •Consume metformin for at least 6 months
排除标准
- •Consume other type of anti-diabetic drugs
- •Presenting any food allergy
- •Recent surgery or infections that may affect oral glucose tolerance test
- •Consume other drugs that may affect oral glucose tolerance test
- •Not consuming any anti-diabetic drugs
- •Pre-diabetes (HbA1c 5.7 - 6.4%)
研究组 & 干预措施
Placebo
This arm will be given chicken-flavored soup without any supplements before conducting the oral glucose tolerance test
干预措施: Oral Glucose Tolerance test (75g 2-hour) (Diagnostic Test)
Placebo
This arm will be given chicken-flavored soup without any supplements before conducting the oral glucose tolerance test
干预措施: Placebo (Dietary Supplement)
Whey
This arm will be given chicken-flavored soup containing whey isolate powder before conducting the oral glucose tolerance test
干预措施: Oral Glucose Tolerance test (75g 2-hour) (Diagnostic Test)
House Cricket
This arm will be given chicken-flavored soup containing house cricket powder before conducting the oral glucose tolerance test
干预措施: Oral Glucose Tolerance test (75g 2-hour) (Diagnostic Test)
House Cricket
This arm will be given chicken-flavored soup containing house cricket powder before conducting the oral glucose tolerance test
干预措施: House cricket (Dietary Supplement)
Whey
This arm will be given chicken-flavored soup containing whey isolate powder before conducting the oral glucose tolerance test
干预措施: Whey (Dietary Supplement)
结局指标
主要结局
Blood glucose
时间窗: 120 minutes
Blood glucose concentration measured using glucometer. Participants fingers are pricked and using capillary tube, a drop of the blood is dripped in a test strip before inserted to a glucometer.
次要结局
- Blood insulin(120 minutes)
研究者
JERRY VANLIN
Principal Investigator
University of Malaya