MedPath

Investigating the effect of senna on preparation for colonoscopy

Phase 3
Conditions
colonoscopy preparation.
Registration Number
IRCT20211101052935N1
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
362
Inclusion Criteria

People more than 18 year-old.
Giving a written consent.
Indications for colorectal cancer screening, include: average-risk screening, increased-risk screening (patients with one or more first degree relative[s] with colorectal cancer [CRC] or colorectal adenomas, hereditary CRC syndromes), positive fecal occult blood test, documented iron deficiency anemia in men or postmenopausal women.
Lower gastrointestinal symptoms such as unexplained chronic clinically significant diarrhea, or unexplained involuntary weight loss.
Abnormal abdominal imaging such as abnormalities detected on barium enema, abdominal computed tomography and etc.

Exclusion Criteria

Hypersensitivity to polyethylene glycol or senna
Taking laxatives within one week prior to colonoscopy
Previous colonic resection surgery
Known or suspected bowel obstruction
Prior history of colonoscopy

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Quality of colon preparation. Timepoint: During colonoscopy (within first 24 hours after use regimens). Method of measurement: Endoscopist report based on BBPS (Boston Bowel Preparation Scale).
Secondary Outcome Measures
NameTimeMethod
Adverse effects of preparation regimens. Timepoint: While taking the drug until colonoscopy. Method of measurement: patients report.
© Copyright 2025. All Rights Reserved by MedPath