CONDOR Study of Osteonecrosis of the Jaws (TMJ)
- Conditions
- Osteonecrosis of the Jaw
- Registration Number
- NCT01130389
- Lead Sponsor
- Dental Practice-Based Research Network
- Brief Summary
The purpose of this study was to examine risk factors for osteonecrosis of the jaw (ONJ), including the possible association with bisphosphonates (BPs). This study used the research infrastructure from the three NIDCR-funded dental practice-based research networks (DPBRN, PEARL, PRECEDENT). De-identified data from the DPBRN were merged with comparable de-identified data from PEARL and PRECEDENT to form a single trans-PBRN data set used for analysis.
- Detailed Description
The aims of this study were to (1) test the hypothesis that (BP) treatment is a risk factor for (ONJ); (2) to test the hypothesis that dental diseases (particularly periodontal disease), and invasive dental procedures such as dental extractions are true risk factors for (ONJ).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 309
- participants directly involved in this study were patients of dentists from the dental practice based research networks (DPBRN, PEARL, PRECEDENT).
- participants with a history of sickle cell anemia
- participants with a history of external severe trauma to the jaws
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (5)
Health Partners Research Foundation
🇺🇸Minneapolis, Minnesota, United States
Kaiser Permanente Center for Health Research
🇺🇸Portland, Oregon, United States
Health Partners Dental Group
🇺🇸Minneapolis, Minnesota, United States
University of Alabama at Birmingham
🇺🇸Birmingham, Alabama, United States
Permanente Denrtal Associates
🇺🇸Portland, Oregon, United States