NCT00858585已完成不适用
Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer: Concordance Study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 149
- 试验地点
- 1
- 主要终点
- Single nucleotide polymorphisms
研究概览
简要总结
This study will examine genes in three different tissues and look for similarities and differences between normal cells and cancer cells. The tissues to be studies come from blood, lymph node and cancer.
详细描述
Subjects will be given an informed consent to read and sign The medical chart will be reviewed for diagnosis and treatment history Blood (about 4 tablespoons) will be drawn at a clinically available time. The lymph node and breast tumor tissue in the University of Michigan pathology repository will be used for research purposes
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age at least 18 years of age
- •Able to read and sign the informed consent
- •Able to provide specimens: one blood draw for white blood cells, provide permission to use tissue already collected.
排除标准
- 未提供
结局指标
主要结局
Single nucleotide polymorphisms
时间窗: time-independent
Determine single nucleotide polymorphism concordances between the three DNA specimen sources
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
已完成
不适用
Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic CancerBone DiseasesMetastasesOsteonecrosisBisphosphonate-Associated Osteonecrosis of the JawNCT01325142University of Michigan271
已完成
不适用
CONDOR Study of Osteonecrosis of the Jaws (TMJ)Osteonecrosis of the JawNCT01130389Dental Practice-Based Research Network309
终止
不适用
Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish PopulationNeural Tube Defects (NTDs)Facial Cleft DefectHereditary Oral CleftsNCT00341068National Human Genome Research Institute (NHGRI)7,451
Unknown
不适用
Clinical and Molecular Characterisation of Orofaciodigital Syndromes and Other Clinical Phenotypes Secondary to Mutations in the OFD1 GeneOrofaciodigital SyndromesNCT01962129Centre Hospitalier Universitaire Dijon133
Unknown
不适用
Genetic Examination of Patients With Primary Multiple HerniaMultiple HerniaNCT00979095Herlev Hospital60
