Prevention of knee Osteoarthritis in Overweight Females

Not Applicable

Completed

• Conditions: Osteoarthritis in overweight females; Musculoskeletal Diseases; Osteoarthritis, obesity

• Registration Number: ISRCTN42823086
• Lead Sponsor: Erasmus Medical Centre (Netherlands)

Brief Summary

1. 2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/23429925 2. 2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24774470 3. 2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24706992 4. 2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/25278062 5. 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25891749 6. 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25818496 7. 2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26806185 8. 2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/27305950 9. 2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/26866630 10. 2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/26521011 11. 2016 results in: http://www.ncbi.nlm.nih.gov/pubmed/26748391 12. 2017 results in: http://www.ncbi.nlm.nih.gov/pubmed/28431145 13. 2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/31300578 (added 15/07/2019)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2006-06-29
• Study Completion: 2012-04-01
• Last Update Posted: 26 August 2019

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 407

Inclusion Criteria

Women aged 50 - 60 years who are overweight (body mass index [BMI] of 27 kg/m^2 or more)

Exclusion Criteria

Amended as of 03/12/2008: point six of the exclusion criteria has been amended as follows:
6. Contraindication for magnetic resonance (MR) imaging

Initial information at time of registration:
1. Knee osteoarthritis (OA)
2. Knee pain indicating knee OA
3. Radiological signs indicating knee OA (Kellgren-Lawrence index of 2 or more)
4. Positive for knee OA according to the American College of Rheumatology (ACR) criteria for knee OA
5. Presence of severe co-morbidity
6. Pacemaker
7. Current use of glucosamine sulphate
8. Not being able to communicate in the Dutch language

Study & Design

• Study Type: Interventional
• Study Design: Not specified