Study to compare continuous erector spinae plane block and thoracic epidural on pain after lung surgery

Phase 3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/07/044362
• Lead Sponsor: Nizams institute of medical sciences

Brief Summary

This is a prospective randomised controlled double blinded study comparing the analgesic efficacy of thoracic epidural analgesia against ultrasound guided continuous erector spinae plane block( ESPB) in post thoracotomy patients. After obtaining written approval, the patients will be randomised into intervention (receiving ESP block) and control group (receiving thoracic epidural analgesia). The ultrasound guided ESPB and thoracic epidural analgesia will be performed before the induction of general anaesthesia. General anaesthesia will be conducted according to the institutional protocol. In postoperative period, the degree of pain will be assessed using VAS on a scale of 0 indicating no pain and 10 indicating the most severe pain ever experienced. Patient will receive rescue analgesia when VAS was > or equal to 4 or on demand. The time to first administration of analgesic will be noted. Postoperative pulmonary function tests and total 48-hour analgesic requirement will also be recorded.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-08
• Last Update Posted: 2022-07-13

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• ASA physical status: 2,3 2.
• Age Group: Adults and older adults (18-60 years) 3.
• Both sexes.

Exclusion Criteria

• Patients allergic to the drugs used in the study 2.
• Patients with diabetic neuropathy, psychiatric illness, and coagulation disorders 3.
• Patients with severe hepatic or renal insufficiency 4.
• Spinal deformities 5.Infection at the site of injection 6.
• Age <18 and >60 years 7.
• Pregnancy 9.
• Emergency surgery.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post operative analgesia as assessed by Visual Analogue Scale (VAS)pain scores at rest and while coughing at 0, 2, 4, 8, 24 and 48 h postoperatively.	1 year

Secondary Outcome Measures

Name	Time	Method
SPI, Haemodynamics at skin incision, rib retraction	SPI based fentanyl- total intraop fentanyl

Trial Locations

Locations (1)

Nizams institute of medical sciences; 🇮🇳 Hyderabad, TELANGANA, India

Nizams institute of medical sciences

🇮🇳Hyderabad, TELANGANA, India

Dr Sowjanya K

Principal investigator

8639370632

sowjanyakutty0209@gmail.com