Effects of nebulized dexmedetomidine versus nebulized magnesium sulphate on reducing intubation response
Phase 3
- Conditions
- Health Condition 1: H60-H95- Diseases of the ear and mastoid process
- Registration Number
- CTRI/2024/07/070396
- Lead Sponsor
- Yuvaraj karthikeyan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients undergoing elective surgery and belonging to ASA physical status I to II
Exclusion Criteria
Patients with difficult airway, uncontrolled hypertension, heart disease with ejection fraction less than 40%, body mass index more than 35 kg/m2, history suggestive of hypersensitivity to drugs used during the study, bradycardia- heart rate less than 50 beats per minute, any heart block, hepatic impairment, renal impairment and pregnancy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the hemodynamic effects of preoperative nebulized dexmedetomidine and nebulized magnesium sulphate on laryngoscopy and intubation stress response attenuationTimepoint: 1 hour
- Secondary Outcome Measures
Name Time Method To assess the requirement of additional anesthetic drugs(fentanyl, propofol)in order to maintain the hemodynamics within 20% of baseline valuesTimepoint: 1 hour