Community-based Intervention to Address Antibiotic Resistance: An Embedded Mixed-methods Interventional Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 3,800
- 试验地点
- 3
- 主要终点
- The intervention package proposed is expected to improve the awareness of the participants on appropriate use of antibiotics, and on the adverse effects of antibiotic resistance. It is expected that the proportion of antibiotic resistance will not increase further in the intervention clusters as compared to the control clusters.
研究概览
简要总结
Background:
Antibiotic resistance is a global threat that occurs naturally but misuse and overuse of antibiotics in humans and animals is accelerating the process and requires ‘one health’ approach to mitigate the situation.
Novelty:
Considering ‘one health’ approach in the proposed study, it is the novel concept for implementation in Indian context. The proposed study would generate evidence on burden of antibiotic resistance, awareness and practices of proper antibiotic consumption among community members in West Bengal. The intervention package proposed in this study will be a novel intervention, which can be integrated with the existing healthcare delivery system as well.
Obje*****ctive**s:*
To evaluate the changes in awareness and practices related to antibiotic consumption, and the proportion of antibiotic resistance after the intervention.
Methods:**
The proposed study will be an embedded mixed methods interventional community-based study to be conducted in greater Kolkata region and West Medinipur district among adults (≥ 18 years of age) who will give consent for participation, and residing in a particular area for more than 10 years. Intervention in the form of behavioral intervention package, targeting awareness, perceived severity, and perceived susceptibility regarding the issue of Antibiotic resistance will be developed and implemented. Data collection in the form of survey, observation, in-depth interview, collection of human, animal and environment sample will be carried out.
Expected outcome:
The intervention package proposed is expected to improve the awareness of the participants on appropriate use of antibiotics, and on the adverse effects of antibiotic resistance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Permuted block randomization, variable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Individuals suffering from any symptoms of systemic infection (e.g., fever, pain in the abdomen, diarrhea, urinary problems, cough and cold, etc.) within the last 3 months of the field survey.
排除标准
- •Critically ill, cancer patients, or bed-ridden patients
- •Individuals diagnosed to be immunocompromised
- •Individuals on immunosuppressive therapy
- •Respondents diagnosed with any psychiatric illness.
结局指标
主要结局
The intervention package proposed is expected to improve the awareness of the participants on appropriate use of antibiotics, and on the adverse effects of antibiotic resistance. It is expected that the proportion of antibiotic resistance will not increase further in the intervention clusters as compared to the control clusters.
时间窗: 3 months after the intervention delivery
次要结局
- It is expected that the proportion of antibiotic resistance will not increase further in the intervention clusters as compared to the control clusters.(3 to 4 months after the intervention delivery)