Hypocaloric nutrition in intensive care medicine and its clinical relevance
Phase 3
- Conditions
- Critically ill internal patients, who need parenteral nutrition during the first seven days of acute illness
- Registration Number
- DRKS00000104
- Lead Sponsor
- niversitätsklinikum Leipzig AöR, Department für Innere Medizin, Interdisziplinäre Internistische Intensivmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
critically ill medical patients, which require artificial nutrition for at least three days
Exclusion Criteria
- underweight patients (defined as a body mass index of less than 19) or pre-existent malnutrition
- refusal to participate in the study by the patient or guardian
- probable length of ICU stay less than 3 days
- no need for artificial nutrition
- pregnancy
- immune suppression
- transplantation
- chemotherapy
- surgical patients
- burns
- age under 18 years or over 80 years
- participation in another trial
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of nosocomial infection (microbiological diagnosis of tracheal secretion, urin and blood culture, clinical and radiological criteria of nosocomial infection)
- Secondary Outcome Measures
Name Time Method - Glycemic control and insulin demand (Blood glucose control every 3 hours, documentation of insulin demand to maintain a blood glucose level of 8-10 mmol/l)<br>- intensive care unit survival<br>- hospital survival<br>- 28-day survival<br><br>Data acquistion from hospital charts, telephone interview if patient discharged before day 28 (questionnaire)