The impact of hypocaloric diet with intensive insulin therapy on mortality and morbidity in adult critically ill patients

Completed

• Conditions: Nutritional, Metabolic, Endocrine; hypocaloric diet with intensive insulin therapy; Intensive care, critically ill patients

• Registration Number: ISRCTN96294863
• Lead Sponsor: King Abdulaziz City for Science and Technology (KACST) (Saudi Arabia)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-07-31
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 240

Inclusion Criteria

1. Patients receiving nasogastric tube feeding
2. Aged >18 years
3. Staying >48 hours in Intensive Care Unit (ICU)

Exclusion Criteria

1. Refused consent
2. Terminal illness
3. DNR (Do Not Recussitate; no code, no escalation) in first 48 hours of admission
4. Enteral feeding cannot be started within 48 hours
5. Total Parentral Nutrition (TPN)
6. Oral feeding
7. Liver transplant
8. Seizures within last 6 months
9. Expected to stay less than 48 hours
10. Age less than 17 years
11. Readmission
12. Brain dead within 48 hours
13. Pregnancy
14. Post cardiac arrest
15. Enrolled in another study
16. Hypoglycemic coma
17. Blood glucose less than 6.1mmol in first 48 hours
18. Type 1 diabetes

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ICU, 28 day and Hospital mortality.

Secondary Outcome Measures

Name	Time	Method
1. ICU length of stay <br>2. Duration of mechanical ventilation <br>3. Incidence of nosocomial infections