Metabolism and Nutrition in Neurointensive Care
Recruiting
- Conditions
- ICU acquired weakness (ICUAW)
- Registration Number
- DRKS00031472
- Lead Sponsor
- MU Klinikum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 500
Inclusion Criteria
Neurological disease as primary ICU admission diagnosis
- Expected length of ICU stay more than 5 days (according to judgement of treating clinicians)
- Inclusion <48 hours after ICU admission
- Indication for clinical nutrition (according to local SOP/guidelines)
Exclusion Criteria
- Age < 18 years
- Prior ICU treatment > 24 hours during the same hospital admission
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Modified Rankin Scale (mRS) [time frame 90 days]<br>Glasgow Outcome Scale Extended (GOSE) [time frame 90 days]
- Secondary Outcome Measures
Name Time Method ICU length of stay<br>Duration of mechanical ventilation<br>Nosocomial infection<br>Calories administered/calories calculated<br>Protein administered/protein calculated<br>Nitrogen balance<br>Glycemic control<br>3-Methylhistidin<br>CSA M. temporalis<br>CSA M. rectus femoris<br>Quality of Life (EQ-5D-5L)<br>Modified Rankin Scale 0-2 vs 3-6