Metabolic, neuronal and immunological regulation of body weight
Recruiting
- Conditions
- Participants within all BMI-categories ( underweight up to obesity grade III) are eligible for participation in this basic research study.
- Registration Number
- DRKS00027068
- Lead Sponsor
- niversität zu Köln, Poliklinik für Endokrinologie, Diabetologie und Präventivmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 800
Inclusion Criteria
Age equal to or above 18 years
- Ability to understand and willingness to comply with study procedures, and to provide written informed consent
- Fasted for at least eight hours (i.e. overnight)
- General prerequisites for MR measurements (see Selbstauskunft zu MRT für Probanden”) if applicable
Exclusion Criteria
- Severe dementia
- Consuming illness with limited life expectancy
- Poor knowledge of the German language
- MRI contraindication (claustrophobia, large area tattoos, very poor eyesight) if applicable
- Women: pregnancy, nursing
- If the inclusion criteria are not applicable
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main objective of this study is to identify physiological mechanisms of weight regulation. Focus is, among others, on endocrinological, neurobiological, immunological, and psychosomatic mechanisms. Measurement time-points depend on the weight development of each participant, as measurements only take place on days of medically indicated assessments (for example, a participant undergoing bariatric surgery has medical appointments and hence measurements pre-surgery, 6 months after surgery, 12 months after surgery and then once per year). Measurements include neuropsychological assessments in combination with fMRI, blood value measurements, anthropometric measurements and further questionnaires.
- Secondary Outcome Measures
Name Time Method ot applicable, as this is a basic research study