Effect of Vitamin D on Retinal Changes in Patient With Optic Neuritis by Optic Coherence Tomography

Phase 2

• Conditions: Optic Neuritis
• Interventions: Drug: Vitamin D; Drug: Vitamin D withheld

• Registration Number: NCT01465893
• Lead Sponsor: Isfahan University of Medical Sciences

Brief Summary

This study examines the effect of vitamin D on Retinal changes in patient with optic Neuritis.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-07
• Study First Submitted: 2011-10-28
• Status Verified: 2011-11
• Study First Submitted QC: 2011-11-04
• Study First Posted: 2011-11-06
• Last Update Submitted: 2011-11-21
• Last Update Posted: 2011-11-22
• Primary Completion: 2012-07
• Study Completion: 2012-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• age 15-50 years
• no history of demyelinative events
• level of vitamin d below 20 ng/ml
• no pass 10-32 day from starting symptom

Exclusion Criteria

• using vitamin D supplement

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
vitamin D	Vitamin D	vitamin d 50000/w
control	Vitamin D withheld	follow up

Primary Outcome Measures

Name	Time	Method
measurement Retinal nerve fiber layer (RNFL) thickness by OCT	10-32 days after optic neuritis

Secondary Outcome Measures

Name	Time	Method
measurement RNFL thickness by OCT	6 months after optic neuritis

Trial Locations

Locations (1)

Isfahan Medical University; 🇮🇷 Tehran, Iran, Islamic Republic of