Whole-Body Vibration Treatment in Breast Cancer Survivors on Aromatase Inhibitor Therapy

Not Applicable

Recruiting

• Conditions: Breast Cancer; Osteopenia; Cancer - Breast; Musculoskeletal - Osteoporosis

• Registration Number: ACTRN12611001094965
• Lead Sponsor: Dr Michael Baker

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-10-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

Currently taking an Aromatase Inhibitor drug for the treatment of breast cancer;
Willing to continue taking any bone altering medications or supplements they were previously taking for the duration of the study, including calcium and vitamin D;
Able to stand unassisted for sustained periods of time (i.e. 20 minutes)

Exclusion Criteria

Currently taking bisphosphonate medication;
Cognitive impairment;
Contraindications to vibration platform training (including pacemaker and fracture within the past six months);
Diagnosis of bone metastasis, and
Diagnosis of diseases other than osteoporosis affecting bone

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Marker of bone formation - Serum Type 1 Procollagen N-terminal Propeptide (P1NP)[Baseline and after 12-weeks of intervention];Marker of bone resorption - Urine analysis of N-telopeptide X/Creatinine (NTx/Cr)[Baseline and after 12-weeks of intervention]

Secondary Outcome Measures

Name	Time	Method
Fatigue - FACIT Fatigue Scale[Baseline and after 12-weeks of intervention];Physical Activity Levels - Godin Questionnaire[Baseline and after 12-weeks of intervention];Pain - WOMAC Scale and a Visual Analogue Scale[Baseline and after 12-weeks of intervention];Upper and Lower Body Strength - 1 Repetition Maximum assessment of chest press and leg press[Baseline and after 12-weeks of intervention];Physical Function - Standard measures of chair standing, six-minute walk, static balance[Baseline and after 12-weeks of intervention];Body Composition - Dual-energy X-ray absorptiometry[Baseline and after 12-weeks of intervention]