Whole-Body Vibration Treatment in Prostate Cancer Survivors on Androgen Suppression Therapy

Not Applicable

• Conditions: Prostate Cancer; Osteopenia; Cancer - Prostate; Musculoskeletal - Osteoporosis

• Registration Number: ACTRN12612000082808
• Lead Sponsor: Edith Cowan University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-01-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: 50

Inclusion Criteria

Undergoing androgen suppression therapy for prostate cancer
and are within one year of initiation of treatment.
Willing to continue taking any bone altering medications or supplements they were previously taking for the duration of the study, including calcium and vitamin D.
Able to stand unassisted for sustained periods of time (i.e. 20 minutes)

Exclusion Criteria

Currently taking bisphosphonate medication;
Cognitive impairment;
Contraindications to vibration platform training (including pacemaker and fracture within the past six months);
Diagnosis of bone metastasis;
Diagnosis of diseases other than osteoporosis affecting bone

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Marker of bone formation - Serum Type 1 Procollagen N-terminal Propeptide (P1NP)[Baseline and after 12-weeks of intervention];Marker of bone resorption - Urine analysis of N-telopeptide X/Creatinine (NTx/Cr)[Baseline and after 12-weeks of intervention]

Secondary Outcome Measures

Name	Time	Method
Fatigue - FACIT Fatigue Scale[Baseline and after 12-weeks of intervention];Physical Activity Levels - Godin Questionnaire, and sedentary time via domain specific sedentary questionnaire[Baseline and after 12-weeks of intervention];Body Composition - Dual-energy X-ray absorptiometry[Baseline and after 12-weeks of intervention];Physical functioning, 400m walk, static balance, stair climb, repeated chair rise, 6 meter walking tests[Baseline and after 12-weeks of intervention];Upper and Lower Body Strength - 1 Repetition Maximum assessment of chest press and leg press[Baseline and after 12-weeks of intervention];Serum 25-OH vitamin D status, testosterone levels, prostate specific antigen levels[Baseline and after 12-weeks of intervention];Quality of life measured by SF-36, and prostate specific concerns measured by The Expanded Prostate Cancer Index Composite Short Form[Baseline and after 12-weeks of intervention]