It is the study done in lower limb orthopedic surgeries to assess postoperative pain. The study is done to know the efficacy of epidural fentanyl and buprenorphine as an adjuvant to ropivacaine.
Phase 3
- Conditions
- Health Condition 1: - Health Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2023/06/053993
- Lead Sponsor
- Dr Sontakke Mahananda Ramrao
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 All patients posted for lower limb orthopedic surgery.
2 Patients who belongs toAmerican Society of Anaesthesiology grade I andII.
3 Age group 18-80 years.
Exclusion Criteria
1.Patients on opioid or sedative medication in the week prior to the surgery.
2.Patients with history of alcohol or drug abuse.
3.History of coagulation disorders or on anti coagulant drug.
4.Patients who have known allergies to any of test drugs.
5.Known case of respiratory diseases.
6.Contraindications for epidural anaesthesia.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To study the efficacy of epidural fentanyl and buprenorphine as an adjuvant to ropivacaine for post operative analgesia. <br/ ><br>2.To compare the duration of post operative analgesia for ropivacaine with fentanyl and ropivacaine with buprenorphine. <br/ ><br>Timepoint: 1.To study the efficacy of epidural fentanyl and buprenorphine as an adjuvant to ropivacaine for post operative analgesia at baseline. <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method To study systemic side effects of fentanyl and buprenorphineTimepoint: 1.To compare the duration of post operative analgesia for ropivacaine with fentanyl and ropivacaine with buprenorphine for 24 hours. <br/ ><br>