Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula in Acute Respiratory Failure Patients : the Standardized PaO2 / FiO2 Ratio (P /F-st), ROX Index and HACOR
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Respiratory Failure Patients on NIV and HFNC
- Sponsor
- Assiut University
- Enrollment
- 120
- Primary Endpoint
- Determine Golden time for intubation
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Comparison between some predictors of failure of non-invasive ventilation and high flow nasal cannula.
Detailed Description
Delayed intubation after NIV / HFNC failure is associated with high mortality rate in acute respiratory failure patients. There are Many factors to predict early failure but World still searching for new factors and comparing between each ;in order to eatablish best one that achieve the least mortality rate. Little studies about effiecacy of HACOR Score as a predictor of failure in HFNC patients. Little studies about effiecacy of ROX Index as a predictor of failure in NIV ventilating patients.
Investigators
Hussein Makarem
Resident doctor
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Acute respiratory failure patients who need ventilatory Support either NIV or HFNC due to :
- •RR \> 25 cycle / min
- •using accessory muscles and paradoxical breath.
- •PaO2 / FiO2 ratio \< 300
Exclusion Criteria
- •Absolute indication for intubation like coma, haemodynamically unstable... etc
- •Contr-indication of NIV like untreated Pneumothorax.
Outcomes
Primary Outcomes
Determine Golden time for intubation
Time Frame: 1 year
Determine best time for intubation according to some predictors of failure of NIV and HFNC