Predictors of Failure of Non-invasive Ventilation and High Flow Nasal Cannula in Acute Respiratory Failure Patients : the Standardized PaO2 / FiO2 Ratio (P /F-st), ROX Index and HACOR
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 120
- 主要终点
- Determine Golden time for intubation
研究概览
简要总结
Comparison between some predictors of failure of non-invasive ventilation and high flow nasal cannula.
详细描述
Delayed intubation after NIV / HFNC failure is associated with high mortality rate in acute respiratory failure patients.
There are Many factors to predict early failure but World still searching for new factors and comparing between each ;in order to eatablish best one that achieve the least mortality rate.
Little studies about effiecacy of HACOR Score as a predictor of failure in HFNC patients.
Little studies about effiecacy of ROX Index as a predictor of failure in NIV ventilating patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Acute respiratory failure patients who need ventilatory Support either NIV or HFNC due to :
- •RR > 25 cycle / min
- •using accessory muscles and paradoxical breath.
- •PaO2 / FiO2 ratio < 300
排除标准
- •Absolute indication for intubation like coma, haemodynamically unstable... etc
- •Contr-indication of NIV like untreated Pneumothorax.
结局指标
主要结局
Determine Golden time for intubation
时间窗: 1 year
Determine best time for intubation according to some predictors of failure of NIV and HFNC
次要结局
未报告次要终点
研究者
Hussein Makarem
Resident doctor
Assiut University