Detection of central pain processing in patients with Parkinsons's disease
- Conditions
- G20.9
- Registration Number
- DRKS00011207
- Lead Sponsor
- niversitätsklinikum Schleswig-Holstein Campus Kiel
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 75
1) legal competence of the study participants (MOCA > 18), signed informed consent
2) ability to adequate communication and editing of the used questionnaires
3)
a) clinical signs of Parkinson's disease at stadium Hoehn and Yahr 2 - 3
b) abnormal sniffing sticks test
c) hyperechoic substantia nigra at transcranial ultrasonic examination at least at one side (with sufficient ultrasound window); in addition no sign of a secondary or atypical parkinson syndrome
4) in the painful group no other explanation for the occurence of pain is found
1) abuse of alcohol, illegal drugs or medicine in the past (or suspect of the tester)
2) known other neurologic disease, which leads to different sensoric sensation
3) pregnancy and lactation period
4) members of family of the testers
5) membership in an other study for the last four weeks befor the recruitment visit
6) therapy with strong analgesics (WHO -3)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main aim of this study is the detection of abnormal central pain processing in patients with Parkinson's disease
- Secondary Outcome Measures
Name Time Method Differentiation between painful and painless PD syndromes regarding central pain processing