MDD(Mild Cognitive Impairment Delirium Dementia) Cohort

Recruiting

• Conditions: Delirium; Mild Cognitive Impairment; Dementia
• Interventions: Diagnostic Test: Delirium assessment using S-CAM

• Registration Number: NCT05113446
• Lead Sponsor: Keimyung University Dongsan Medical Center

Brief Summary

* Identify the degree of delirium in subjects with mild cognitive impairment and find the risk factors of delirium. Mortality, hospital stay, and medical expenses are analyzed as clinical consequences related to delirium incidence.

* Dementia conversion rate and conversion period of subjects with mild cognitive impairment with delirium and it identifies the effect of delirium on dementia conversion.

* Develop an AI(Artificial intelligence) algorithm for predicting dementia transition in subjects with mild cognitive impairment based on the research results of the 1st, 2nd, and 3rd years.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-07-01
• Study First Submitted: 2021-10-17
• Study First Submitted QC: 2021-10-28
• Study First Posted: 2021-11-09
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-28
• Last Update Posted: 2022-08-01
• Primary Completion: 2022-10-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 163

Inclusion Criteria

• Patients 65 years of age or older who are admitted to a LTC
• Patients diagnosed with mild cognitive impairment by doctors
• Patients with a score of 18 or more and 23 or less on the Mini-Mental State Examination

Exclusion Criteria

• Patients unable to measure the delirium assessment tool, The Short Confusion Assessment Methods (S-CAM) (Inouye, 2014) due to severe vision and hearing problems
• Patients with serious psychiatric or neurological diagnosis,Patients who expire or were transferred on the day of admission -
• Patients receiving emergency treatment at the time of the delirium assessment or unable to measure or intervene with S-CAM due to hospital circumstances

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
MCI(Mild Cognitive Impairment) group	Delirium assessment using S-CAM	* Inclusion criteria : Patients 65 years of age or older who are admitted to a LTC(long-term care) facilities, Patients diagnosed with mild cognitive impairment by doctors, Patients with a score of 18 or more and 23 or less on the Mini-Mental State Examination * Exclusion criteria : Patients unable to measure the delirium assessment tool, The Short Confusion Assessment Methods (S-CAM) (Inouye, 2014) due to severe vision and hearing problems, Patients with serious psychiatric or neurological diagnosis,Patients who died or were transferred on the day of admission, Patients receiving emergency treatment at the time of the delirium assessment or unable to measure or intervene with S-CAM due to hospital circumstances

Primary Outcome Measures

Name	Time	Method
Dementia conversion rate and transition period in participants with mild cognitive impairment	The participant's dementia conversion is checked in units of 1 month, and the period until conversion to dementia is analyzed in units of 12 months for 36 months.	descriptive statistics
Delirium incidence in participants with mild cognitive impairment	The number of subjects evaluated as positive in the delirium assessment using S-CAM for 30 days from the 1st day of study participation is statistically calculated.	descriptive statistics

Secondary Outcome Measures

Name	Time	Method
Risk factors affecting participants' delirium	On the first day of data collection, the characteristics of subjects are collected through medical records. After 12 months, the risk factors affecting the occurrence of delirium among the characteristics of the subject are analyzed.	Logistic Regression
healthcare costs	From the healthcare costs consumed during the hospital length of stay, the direct healthcare costs used only for treatment are calculated in won units and analyzed in units of 12 months.	Linear Regression
Mortality	It is statistically calculated in 30-day, 60-day, 12-month, 24-month, and 36-month increments.	Kaplan-Meier survival, Cox proportional hazard regression, Logistic Regression
hospital length of stay	The period from hospitalization to discharge is calculated in days and analyzed in units of 12 months.	Linear Regression

Trial Locations

Locations (2)

Gunsan Chamsarang long-term care (LTC) facilities; 🇰🇷 Daegu, Jeollabuk-do, Korea, Republic of

Yangsan Seoul long-term care (LTC) facilities; 🇰🇷 Daegu, Gyeongsangnam-do,, Korea, Republic of