MedPath

Comparison of efficacy of two ophthalmic drops on decreasing intraocular pressure

Not Applicable
Conditions
Glaucoma.
Glaucoma, Glaucoma suspect
H40, H40.0
Registration Number
IRCT2015042021875N1
Lead Sponsor
Vice chancellor for research and technology of Islamic Azad University of Shahrood
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Presence of open angle glaucoma symptoms; ocular hypertension includes patients with increased IOP; glaucomatous cupping (cup to disc ratio between 0.4 - 0.7; disc-cup asymmetry>0.2; notching of the rim; enlargement of the cup; bleeding of the rim of the disc; degeneration of the nerve fiber layer)
Exclusion criteria:
Secondary causes of increasing IOP; cup to disc ratio>0.7; IOP>30 mmHg in each stage of the disease; existing of any other ocular disorder except glaucoma; corrected vision less than 20/50; bradycardia; asthma; COPD; consumption of any drug affecting IOP for example beta blockers, corticosteroids, carbonic anhydrase inhibitors, nitrates and alpha 2 agonists; discontent of patient.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Tonometry. Timepoint: Before intervention, if the first wash out period is needed every 2 weeks during 4 weeks, at the end of the first week, the first and third month, every 2 weeks during 4 weeks in the second wash out period and at the end of the first week, the first and third month after the second wash out period. Method of measurement: Applanation Haag-Streit tonometer.
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath