Comparison of efficacy of two ophthalmic drops on decreasing intraocular pressure
- Conditions
- Glaucoma.Glaucoma, Glaucoma suspectH40, H40.0
- Registration Number
- IRCT2015042021875N1
- Lead Sponsor
- Vice chancellor for research and technology of Islamic Azad University of Shahrood
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Presence of open angle glaucoma symptoms; ocular hypertension includes patients with increased IOP; glaucomatous cupping (cup to disc ratio between 0.4 - 0.7; disc-cup asymmetry>0.2; notching of the rim; enlargement of the cup; bleeding of the rim of the disc; degeneration of the nerve fiber layer)
Exclusion criteria:
Secondary causes of increasing IOP; cup to disc ratio>0.7; IOP>30 mmHg in each stage of the disease; existing of any other ocular disorder except glaucoma; corrected vision less than 20/50; bradycardia; asthma; COPD; consumption of any drug affecting IOP for example beta blockers, corticosteroids, carbonic anhydrase inhibitors, nitrates and alpha 2 agonists; discontent of patient.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tonometry. Timepoint: Before intervention, if the first wash out period is needed every 2 weeks during 4 weeks, at the end of the first week, the first and third month, every 2 weeks during 4 weeks in the second wash out period and at the end of the first week, the first and third month after the second wash out period. Method of measurement: Applanation Haag-Streit tonometer.
- Secondary Outcome Measures
Name Time Method