The effect of Intrathecal Atropine to prevent Nausea & Vomiting after surgeries due to use Intrathecal Morphine in lower limb surgeries
Phase 2
- Conditions
- Spinal Anesthesia.local anaesthetics
- Registration Number
- IRCT2013012012204N1
- Lead Sponsor
- Vice chancellor for research, Qazvin University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Participants including major eligibility criteria:
The patients aged from 40-70 years
Participants excluding major eligibility criteria:
Patients with history Neurologic disease and Neuromuscular; Diabetes Mellitus; Patients with Neuropathy Peripheral; Infection in site of injection; Sensitivity to Local Anesthesia; Patients with Vomiting and Nausea before surgery or receiving 48 hours before surgery Anti Vomiting and Nausea; Women in period of mense
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of Vomiting and Nausea. Timepoint: Incidence of Nausea and Vomiting were studied in patients within 24 hours after injection of Atropine: Hourly up to 6 hours, Then 6 hours later and Finally 12 hours later. Method of measurement: With checklist: Mild; Moderate; Severe.
- Secondary Outcome Measures
Name Time Method Heart Rate. Timepoint: 3,5,10,15 Minutes after Spinal Anesthesia with receiving Atropin Interathecal. Method of measurement: Heart Rate per minute.;Blood Pressure. Timepoint: 3,5,10,15 Minutes after Spinal Anesthesia with receiving Atropin Intrathecal. Method of measurement: Blood volume pump by heart.;With out pain period. Timepoint: Intrathecal Morphine-Induced Analgesia was studied in 2 hours intervals for 12 hours after injection. Method of measurement: With checklist.