Emollient creams for face and body improve eczema in children with atopic dermatitis and help to restablish the normal skin flora

Phase 4

Completed

• Conditions: Atopic Eczema; Skin and Connective Tissue Diseases

• Registration Number: ISRCTN24922464
• Lead Sponsor: Isdin

Brief Summary

2016 results in https://clinical-pediatrics-dermatology.imedpub.com/barrier-repair-therapy-in-atopic-eczemaeffects-of-isoleucine-rhamnosoftceramides-and-niacinamide-facial-and-bodycreams-on-clinical.php?aid=8391 (added 13/05/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-09-30
• Study Start: 2015-10-16
• Last Update Posted: 24 May 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

1. Aged between 2 and 18 years
2. Mild to moderate atopic eczema according to Hanifin diagnostic criteria

Exclusion Criteria

1. Severe form of atopic eczema
2. Use of corticosteroids, calcineurin inhibitors or systemic or topical antibiotics in the 4 weeks prior to enrollement

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Eczema severity is measured using the Eczema Severity Index score (4-point scale) at baseline, week 4 and week 8<br> 2. Itch intensity evaluated by a 10-cm Visual Analogue Scale at baseline, week 4 and week 8<br>

Secondary Outcome Measures

Name	Time	Method
Staphylococcus aureus skin colonization is obtained from lesions using skin swabs at baseline and 2 months.