Influencing Factors of Cerebrovascular Disease and Cognition in Hemodialysis Patients: an Observational Study

Huashan Hospital1 site in 1 country20 target enrollmentJune 1, 2020

ConditionsHemodialysis Cognitive Impairment Cerebrovascular Disorders

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Hemodialysis
Sponsor: Huashan Hospital
Enrollment: 20
Locations: 1
Primary Endpoint: cerebrovascular disease
Status: Recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

In this observational study, the investigators evaluate the influencing factors of cerebrovascular disease and cognition in hemodialysis patients.

Registry

clinicaltrials.gov

Start Date

June 1, 2020

End Date

May 31, 2025

Last Updated

2 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Huashan Hospital

Responsible Party

Principal Investigator

Chen Jing

Professor

Huashan Hospital

Eligibility Criteria

Inclusion Criteria

•maintenance hemodialysis patients who are younger than 85 years old and older than 50 years old, regardless of gender
•dialysis vintage is greater than 3 months;

Exclusion Criteria

•Those with severe infection and anemia (Hb \<60g / L);
•Those with severe mental illness, metabolic diseases and immune system diseases;
•Patients with abnormal liver function

Outcomes

Primary Outcomes

cerebrovascular disease

Time Frame: 5 years

Magnetic resonance images will be used to determine the severity of white matter hyperintensity, using the Scheltens scale. Score 2 or more is abnormal.