Erector Spinae Plane Block vs. iPACK Block With Adductor Canal Block for Total Knee Arthroplasty
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Opioid consumption
研究概览
简要总结
Effect of Erector Spinae Plane Block and iPACK block with Adductor Canal Block on pain management, and NLR and PLR following knee arthroplasty
详细描述
Knee arthroplasty is one of the most common orthopedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prosthesis. Regional anesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.
In recent years, the influence of regional anesthesiology on reducing the inflammatory response after surgical procedures has been emphasized. However, very few studies have evaluated the effect of various methods of anesthesia on the NLR.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with ASA classification I-III,
- •Aged 20-100 years,
- •scheduled for knee arthroplasty under spinal anaesthesia
排除标准
- •Patients who have a history of bleeding diathesis,
- •Take anticoagulant therapy,
- •have a History of chronic pain before surgery,
- •have Multiple trauma,
- •cannot assess their pain (dementia),
- •have been operated on under general anaesthesia,
- •have an infection in the area
- •do not accept the procedure
研究组 & 干预措施
Placebo
Only spinal anaesthesia - No peripheral nerve block
干预措施: Control Test - spinal anesthesia (Drug)
Erector Spinae Plane Block
spinal anaesthesia and unilateral ultrasound guided erector spinae plane block - 20ml 0.2% ropivacaine
干预措施: Ropivacaine 0.2% Injectable Solution ESPB (Drug)
Infiltration Popliteal Artery and Capsule of the Knee and Adductor Canal Block
spinal anaesthesia and ultrasound guided Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee (iPACK) block - 20ml 0.2% ropivacaine
- ultrasound guided Adductor Canal Block - 10ml 0.2% ropivacaine
干预措施: Ropivacaine 0.2% Injectable Solution iPACK+ACB (Drug)
结局指标
主要结局
Opioid consumption
时间窗: 48 hours
Total opiate consumption after surgery
次要结局
- Numerical Rating Scale [range 0:10](24 hours after surgery)
- first need of opiate(48 hours)
- NLR(24 hours postoperatively)
- PLR(24 hours postoperatively)
- Quadriceps muscle strength assessed using medical research council scale [range 0:5](24 hours after surgery)