Urinary Concentration After Salmeterol in Well-trained Men and Females
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Urine concentration
研究概览
简要总结
The purpose of the project is to investigate urine concentration after inhalation of salmeterol. This will be examined following acute physical activity under both normal conditions and heated conditions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Sequential
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Inclusion Criteria:
- •Age 18-40
- •Physically active >5 hours a week
- •Maximum oxygen uptake classified as high or very high
排除标准
- •Active smoker currently or within the past 5 years
- •Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
- •Chronic or acute illness deemed by the responsible study physician to affect the test parameters
- •Deviation from the study protocol
- •Lean mass index >21 kg/m²
- •Pregnancy
- •Blood donation during the past 3 months
研究组 & 干预措施
Normal conditions
Urine samples collected after various performance tests in normal conditions
干预措施: Normal conditions (Other)
Heated conditions
Urine samples collected after various performance tests in heated conditions
干预措施: Heated conditions (Other)
Salmeterol inhalation and urine samples
Participants are administered daily salmeterol inhalation from an MDI device and are required to collect spot urine samples at home.
干预措施: Salmeterol inhalation and urine samples (Drug)
结局指标
主要结局
Urine concentration
时间窗: Through study completion, an average on 1 week
Difference in urine concentration with salmeterol administered before performance tests in different conditions
次要结局
未报告次要终点
研究者
Morten Hostrup, PhD
Associate Professor
University of Copenhagen