Skip to main content
Clinical Trials/NCT07261852
NCT07261852
Not yet recruiting
Not Applicable

Effects of Muscle Strength Training in Lower Limb Amputee Patients

University of Gran Rosario0 sites18 target enrollmentStarted: November 30, 2025Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Sponsor
University of Gran Rosario
Enrollment
18
Primary Endpoint
Changes in Funcionality

Overview

Brief Summary

This study is a clinical trial that evaluates the best treatment option using a strength training protocol and an endurance training protocol in patients with lower limb amputations who use prostheses. The protocol consists of 6 weeks of strength training and 6 weeks of endurance training, with a 1-month washout period between the two.

Detailed Description

The assessments in this study focus primarily on strength, using a dynamometer and the 5 RM, functionality, using the AMP scale, mobility, using the TugTest, quality of life, using the WHOQOL-BREF, and perception of change, using the GROC.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 75 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients with unilateral lower limb amputation
  • Transtibial and/or transfemoral amputation
  • Prosthetized
  • Aged 18 to 75 years
  • Who sign the informed consent form

Exclusion Criteria

  • That they are unable to complete the initial assessment
  • That they undergo further secondary training

Outcomes

Primary Outcomes

Changes in Funcionality

Time Frame: day 1, day 18 (last day of week 6), day 1 (after the wash out) and day 24.

It is assessed using the TUG test, which requires patients to get up from a chair, walk 3 meters, turn around, walk back to the chair, and sit down again. Patients will receive the following instructions: "Get up on the word 'go,' walk to the tape, turn around, walk back to the chair, and sit down."

Changes in quality of life

Time Frame: day 1, day 18 (last day of week 6), day 1 (after the wash out) and day 24.

It is assessed using a self-administered questionnaire called WHOQOL-BREF, which provides a profile of the person's perceived quality of life.

Secondary Outcomes

  • Changes in Maximum isometric muscle strength(day 1, day 18 (last day of week 6), day 1 (after the wash out) and day 24.)
  • Changes on Movility(day 1, day 18 (last day of week 6), day 1 (after the wash out) and day 24.)
  • Change in Global percepcion of change(assessments were performed at the end each protocol. day 18 and day 24)

Investigators

Sponsor
University of Gran Rosario
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Gabriela Dell Elce

principal investigator

University of Gran Rosario

Similar Trials