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Clinical Trials/NCT01074827
NCT01074827
Completed
Not Applicable

Strength Training or Treadmill Walking? A Randomized Control Study on the Effect on Gait in Multiple Sclerosis

St. Olavs Hospital1 site in 1 country28 target enrollmentStarted: March 2010Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
St. Olavs Hospital
Enrollment
28
Locations
1
Primary Endpoint
Walking ability

Overview

Brief Summary

The objective of this study is to evaluate the effect of strength training for the lower extremities and treadmill training on walking ability in persons with Multiple Sclerosis. The study is a randomized control trial with two groups and the intervention is 8 weeks of intensive strength training or treadmill walking. Primary outcome measure is walking ability, secondary outcome measures are balance, work economy and strength.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Diagnosed with Multiple Sclerosis,classified as relapsing remitting,or primary/secondary progressive
  • Expanded Disability Status Scale (EDSS)score of ≤ 6
  • Reduced walking ability (subjectively experienced)

Exclusion Criteria

  • persons with a level of ataxia, clinically assessed, that would affect their ability to perform the training.
  • spasticity requiring stretching og treatment with baclofen.
  • Other, not MS-related, conditions affecting walking ability.

Outcomes

Primary Outcomes

Walking ability

Time Frame: 8 weeks

Secondary Outcomes

  • Work economy O2(8 weeks)
  • Strength(8 weeks)
  • Balance(8 weeks)

Investigators

Sponsor
St. Olavs Hospital
Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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