The frequency of heart artery disease in the siblings of young heart attack patients and the utility of using computer topography (CT) heart scans as a screening test to detect heart artery disease.

Not Applicable

Completed

• Conditions: Coronary heart disease; Cardiovascular - Coronary heart disease

• Registration Number: ACTRN12614000105640
• Lead Sponsor: Western Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-01-29
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Young asymptomatic individuals (male with age between 30-55 and female with age between 30-60) with a history of an acute MI (AMI) in a sibling before 55 years of age for both sexes will be recruited.

Exclusion Criteria

Clinical exclusion criteria are known history of CHD (positive findings on previous functional test or invasive coronary angiogram, history of prior MI or coronary revascularisation), age younger than 30 for both sexes, age older than 55 for male and 60 for female, and refusal to consent. Individuals with contrast or Dobutamine allergy, chronic renal impairment (eGFR <60 mls/min), atrial fibrillation or frequent ventricular ectopics, thyrotoxicosis, pregnancy, ventricular pacing, left bundle branch block or known severe valvular disease will be excluded.

Study & Design

• Study Type: Observational
• Study Design: Not specified