Coronary artery disease in Aboriginal and Torres Strait Islander people

Not Applicable

Recruiting

• Conditions: Coronary artery disease; Public Health - Epidemiology; Acute Coronary Syndrome; Cardiovascular - Coronary heart disease; Chest Pain

• Registration Number: ACTRN12621000232831
• Lead Sponsor: Dr Katrina Starmer

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-04
• Last Update Posted: 8 March 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Patients will be included it they:
1. Are aged 18 years and above;
2. Identify as Aboriginal and/or Torres Strait Islander; and
3. Present with symptoms of 5 minutes or more in duration consistent with possible ACS
such as chest discomfort or angina equivalent; and/or; emergency physician plans to
evaluate the patient for suspected ACS.

Exclusion Criteria

Patients will be excluded from the research study if:
1. They are pregnant or lactating;
2. They are less than 18 years of age;
3. The researcher feels that recruitment is inappropriate (e.g. Terminal illness);
4. They (or legal representative) are unable or unwilling to provide informed consent;
5. They (or legal representative) refuse to be followed-up by telephone or medical record
review after 7 days, or they are unlikely to be contactable e.g. they will be overseas;
6. They have a clear alternative non-ACS diagnostic cause for symptoms;
7. They have a know allergy or contraindication to iodinated contrast precluding CTCA/ICA;
8. They have a known allergy or contraindication to beta-blockade medication precluding
CTCA/ICA;
9. They have severe or restrictive airways disease or acute exacerbation precluding
CTCA/ICA;
10. They have significant renal impairment precluding CTCA/ICA; or
11. They have been recruited to this research project within the last 12 months.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome will be the proportion of patients diagnosed with significant coronary artery disease as determined by coronary anatomic characterisation on CTCA imaging and/or invasive coronary angiography (ICA). Significant CAD is defined as =/>50% stenosis in one or more coronary vessels determined by either CTCA or ICA.[On initial presentation. ]