CTRI/2020/03/024293Completed未知
Impact of MTHFR, MS and CBS genes polymorphisms and vitamin B6, B9 & B12 supplementations on hyperhomocysteinemia among Ischemic stroke patients.
All India Institue of Medical sciences AIIMS Rishikesh0 sites90 target enrollmentStarted: TBDLast updated:
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Enrollment
- 90
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •1Patients who will be having first-ever Ischemic stroke within 72 hours diagnosed by Neurologist with help of CT/MRI report.
- •2Patients who will be having hyperhomocysteinemi at baseline.
- •3Patients who willbe having normal renal function.
Exclusion Criteria
- •1 Patients who will be suffering from disease Migraine, Alzheimer dementia, Parkinsonââ?¬•s disease are excluded from the study.
- •2Patients with recurrent Ischemic stroke and having significant disabilities are excluded from the study.
- •3Patients who having history of vitamin B6, B12, Folic acid supplementations, sex hormonal preparations like androgens intake and treated for depression, dementia, 6 months prior to attack of Ischemic stroke are excluded from the study.
- •4Patients who having hypothyroidism, psoriasis, malignancies, rheumatoid disease are excluded from study.
- •5Patients who were on treatment with drugs like methotaxate, cyclosporine, theophylline, anticonvulsants like phenytoin, carbamazepine, lipid lowering like cholestyramine, nicotinic acid derivatives (e.g. fenofibrate).
Investigators
Similar Trials
Recruiting
Not Applicable
MTHFR-Gene Polypmorphisms and its prognostic impact for response of radiochemotherapy in rectal cancerC20Malignant neoplasm of rectumDRKS00022818niversitätsklinik für Allgemein- Viszeral und Thoraxchiirurgie, Proktologie der RUB160
Not yet recruiting
Not Applicable
Role of genetic polymorphisms, inflammation and biomarkers in primary and secondary traumatic brain injuryNL-OMON31166niversitair Medisch Centrum Sint Radboud100
Completed
Not Applicable
Polymorphism C677T MTHFR and Folate Intake in Inflammatory BiomarkersOverweight and ObesityNCT03186196Federal University of Paraíba48
Completed
Not Applicable
A Retrospective Cohort Study: The Influence of MTHFR C677T and A1298C on the High-dose Methotrexate-Related Toxicities in Pediatric Patients With Non-Hodgkin LymphomaPediatric NHLNCT04283955Sun Yat-sen University93
Not yet recruiting
Not Applicable
Impact of CYP2A6 and CHRM3 genetic polymorphisms on the PK/PD of pilocarpine in Japanese healthy volunteerss syndromeSjogren's syndromeJPRN-UMIN000010796Oita University Faculty of Medicine30