Study of types of venous Outflow reconstruction in right lobe living donor Liver Transplantatio
Phase 3
- Conditions
- Health Condition 1: K74- Fibrosis and cirrhosis of liverHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2021/09/036589
- Lead Sponsor
- Mettu Srinivas Reddy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Adult patients undergoing their first liver transplantation for chronic liver disease and receiving a right lobe living donor liver graft
Exclusion Criteria
Patients who cannot consent for the study
Patients allergic to CT contrast
Patients undergoing auxiliary transplantation, retransplantation
Patients receiving grafts with no anterior sector outflow reconstruction
Patients receiving grafts recovered with total/sub-total MHV
Patients in whom deceased donor/autologous vein graft for anterior sector outflow reconstruction
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Patency of reconstructed anterior sector veinsTimepoint: 6 weeks after liver transplant
- Secondary Outcome Measures
Name Time Method Cold ischemia time <br/ ><br>Warm ischemia time <br/ ><br>Intra-operative doppler ultrasound flow pattern of right hepatic vein and anterior sector vein <br/ ><br>Final portal pressure <br/ ><br>Timepoint: During liver transplantation surgery;Patency and phasicity of flow in right hepatic vein and anterior sector veinsTimepoint: Post-operative days 1,2,3,5,7,14,30,60,180,365;Post-operative allograft function <br/ ><br>Drain output <br/ ><br>Need for intervention for graft venous outflow or for small for size syndromeTimepoint: Immediate post-operative period