Vitamin D receptor polymorphism in two clinical phenotypes of chronic hepatitis B infection: HBV carrier with low viral load and chronic hepatitis phases

Not Applicable

• Conditions: Vitamin D receptor polymorphismChronic HBV infectionHBV carrier with low viral loadChronic hepatitis; Vitamin D receptor polymorphism; Chronic HBV infection; HBV carrier with low viral load; Chronic hepatitis

• Registration Number: TCTR20191110003
• Lead Sponsor: Department of medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-10
• Study Completion: 2020-05-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

Patients with chronic HBV infection defined by HBsAg positive more than 6 months.

Exclusion Criteria

- pregnancy
- patients with the conditions that may alter the immune system, for example; HIV infection, cancer, autoimmune disease, receiving immunosuppressive drugs and active infection.
- HCV and HIV co-infection
- HBV infected patients with decompensated cirrhosis and hepatocellular carcinoma

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Single nucleotide polyomorphism(SNP) during recruitment real time PCR

Secondary Outcome Measures

Name	Time	Method
Haplotype during recruitment Sequence of SNP