Vitamin D receptor gene polymorphism and left ventricular hypertrophy in chronic kidney disease patients with preserved renal functio
Not Applicable
Completed
- Conditions
- Diseases of The genitoruinary system
- Registration Number
- KCT0000398
- Lead Sponsor
- Samsung Changwon Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 319
Inclusion Criteria
1. stage 2~4 of CKD patients
2. less than 160/100 mmHg of blood pressure at sitting position in
hypertensive patients
3. more than 100 mmHg of systolic pressure at sitting position in
normotensive patients
Exclusion Criteria
Patients with
Uncontrolled hypertension (more than 160/100 mmHg)
Vitamin D supplementation
Renal artery stenosis or primary aldosteronism
Refractory edema
immunosuppressive agents
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Association between vitamin D receptor polymorphism and left ventricular hypertrophy
- Secondary Outcome Measures
Name Time Method association between vitamin D receptor polymorphism and vitamin D concentration;association between vitamin D receptor polymorphism and progression of left ventricular hypertrophy;association between vitamin D receptor polymorphism and progression of kidney dysfunction