Mitochondrial Mutations and AML

Children's Oncology Group0 sites18 target enrollmentFebruary 2009

ConditionsLeukemia

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Leukemia
Sponsor: Children's Oncology Group
Enrollment: 18
Primary Endpoint: Association between clonally expanded somatic mitochondrial DNA mutations and acute myeloid leukemia
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

RATIONALE: Studying samples of blood from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This research study is studying biomarkers in patients with acute myeloid leukemia.

Detailed Description

OBJECTIVES: * To determine whether clonally expanded somatic mitochondrial DNA mutations are associated with acute myeloid leukemia. OUTLINE: Genomic DNA from blood samples obtained at diagnosis, remission, and relapse are analyzed for mitochondrial DNA mutations via PCR.

Registry

clinicaltrials.gov

Start Date

February 2009

End Date

March 2010

Last Updated

10 years ago

Study Type

Observational

Sex

All