The Effect of Bariatric Surgery versus Intensive Medical Therapy on Nutritional Status, Risk of Cardiovascular Disease, Diabetes Remission and Metabolic Diseases in Obese Thai Popultaio
Recruiting
- Conditions
- People living with obesityintensive medical therapy, very low-calorie diet, Roux-en-Y gastric bypass, sleeve gastrectomy, body composition, gut microbiota, diabetes remission, type 2 diabetes
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 400
Inclusion Criteria
1.Obese subjects who will undergo bariatric surgery or receive intensive medical therapy
2.Age 15-70 years
3.ability and willingness to provided informed written consent
Exclusion Criteria
1. End-stage disease such as cancer, cirrhosis Child-Pugh C, or critical/acute illness, 2. Type 1 diabetes mellitus, 3. Use of antibiotics in the previous month, 4. Use of probiotic or prebiotic supplement in the form of tablet or sachet in the previous 14 days, 5. Pregnancy or breast-feeding, 6. Substance abuse, 7. Uncontrolled psychiatric disorders and eating disorders
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in body weight From baseline and at each follow up visit (2-4weeks, 2-month, 3-month, 6-month, 12-month, 18-month, 24-month, then yearly) Weight in kg, percent weight loss, percent excess weight loss, percent BMI loss
- Secondary Outcome Measures
Name Time Method