The long-term effects of bariatric surgery on metabolism, behavior and striatal dopamine receptors

Completed

• Conditions: obesitas; metabolic syndrome

• Registration Number: NL-OMON39639
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 19

Inclusion Criteria

pre-menopausal Caucasian women that took part in our previous study The pleiotropic effects of bariatric surgery

Exclusion Criteria

- use of medication that interferes with dopamine metabolism
- claustrophobia
- pregnancy
- tobacco use (i.e. smokers)
- unwilling or unable to provide informed consent

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- striatal dopamine D2/3 receptor availability</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- plasma levels of several hormones, metabolites and peptides involved in<br /><br>appetite regulation and glucose metabolism<br /><br>- behavioral parameters (measured via questionnaires and computer tasks)</p><br>