Evaluation of Platelet-rich Fibrin / Biphasic Calcium Phosphate Effect Versus Autogenous Bone Graft on Reconstruction of Alveolar Cleft Defect in the Maxillary Arch: Randomized Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- bone height
研究概览
简要总结
P- Maxillary alveolar cleft defects I- Platelet-rich fibrin (PRF) combined with biphasic calcium phosphate (BCP) C- Autogenous bone graft O- Outcome measure : bone height, bone volume, hospital stay, operation duration T- 6 months S- Randomized controlled clinical trial this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch.
详细描述
this study aimed to answer a clinical question whether the use of Platelet-rich Fibrin (PRF) combined with Biphasic Calcium Phosphate (BCP), can be an alternative to autogenous bone graft in reconstruction of alveolar cleft defect in maxillary arch
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 8 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients suffering from maxillary alveolar cleft
- •Patients' age 8 years and older
排除标准
- •Syndromic cases will be excluded
- •Patients suffering from platelets disorders.
研究组 & 干预措施
PRF/ BCP
Biphasic calcium phosphate (BCP)"bioceramic bone substitute combined with platelet rich fibrin PRF
干预措施: PRF/ BCP (Other)
autogenous bone graft
Autogenous bone graft involving utilizing bone obtained from the same individual receiving the graft
干预措施: Autogenous bone graft (Other)
结局指标
主要结局
bone height
时间窗: six months postoperative.
the vertical bone height measured from the most coronal level of the pyriform aperture to the most apical level of the bony bridge.
次要结局
- bone volume(six months postoperative.)
- operation duration(within 4 hours ( the actual number of hours will be determined intra-operative ))
- hospital stay(within 7 days)
研究者
Hebatallah G Samra El-Shamy
resarcher
Cairo University