A Randomised, Crossover Comparison of Nasal Ventilation vs Face Mask in Anesthetised Adults
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Nasotracheal Intubation
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Difference in expired tidal volume of each technique under pressure-controlled mode
- Last Updated
- 7 years ago
Overview
Brief Summary
Nasotracheal intubation(NTI) is commonly used in operations of the mouth, pharynx, larynx and also the neck. While these patients showed higher rates of difficult laryngoscopy. Therefore, duration of apnoea is prolonged and re-oxygenation is inevitable.Mask ventilation is the most fundamental technique in maintaining oxygenation, even when endotracheal intubation is failed. However, the most common complication of NTI is epistaxis, removing the nasotracheal tube could make mask ventilation extremely difficult.So the investigatorsbelieve the ideal approach is ventilation through original nasotracheal tube.Several techniques of supraglottic ventilations through endotracheal tubes have been reported.It remains uncertain whether supraglottic ventilation through inflated nasal RAE endotracheal tube has similar efficiency as mask ventilation after general anesthesia induction. Based on previous clinical experience, the investigators hypothesised that ventilations through inflated nasal RAE endotracheal tube and through facemask were comparable in terms of tidal volume and airway pressure in anesthetized, apnoeic adults.
Forty patients were randomly assigned (sealed envelope method) to face mask(Group A,n=20)or nasal ventilation(Group B,n=20), For A: face mask ventilation followed by nasal ventilation and for B:nasal ventilation followed by face mask ventilation.Measure the tidal volume and air leakage of face mask and nasal ventilation during pressure-controlled ventilation mode and volume-controlled mode, respectively.
Investigators
Yu Sun
Principal Investigator
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Eligibility Criteria
Inclusion Criteria
- •Age between 18-55 years old
- •ASA physical status I and II
- •Requiring general anesthesia with nasal intubation
Exclusion Criteria
- •Respiratory disease,cardiovascular disease, cerebral vascular disease
- •Anticipated Difficult Mask Ventilation(Age\>55 years old, obesity,bearded,edentulous,a history of snoring)
- •The need for emergency surgery
- •Contraindications to nasal intubation
- •Pregnancy
- •Gastric-esophageal reflex or a full stomach
Outcomes
Primary Outcomes
Difference in expired tidal volume of each technique under pressure-controlled mode
Time Frame: 3 breaths of expired tidal volume for each technique
Difference in air leakage of each technique under volume-controlled mode
Time Frame: 3 breaths of air leakage for each technique
Secondary Outcomes
- number of participants with Oxygen Saturation- Reading Below 95%(intraoperative duration of each ventilation technique)
- hemodynamic changes(intraoperative duration of each ventilation technique)
- peak inspiratory pressure(intraoperative duration of each ventilation technique)
- end tidal CO2 partial pressure Reading- Median(intraoperative duration of each ventilation technique)