Cholecalciferol Supplementation in Kidney Failure Study: Effect on Quality of Life and Muscle Strength

Phase 2

Completed

• Conditions: Muscle weakness in patients with kidney failure; Quality of Life in patients with kidney failure; Renal and Urogenital - Kidney disease

• Registration Number: ACTRN12611001260910
• Lead Sponsor: Richard Singer

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2011-12-07
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 88

Inclusion Criteria

Undergoing maintenance therapy with twice or thrice weekly conventional haemodialysis or receiving peritoneal dialysis. Clinically stable.

Exclusion Criteria

Baseline calcidiol level >50nmol/l, baseline hypercalcaemia, chronic granulomatous disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of Life, as assessed by completion of the KDQOL-SF version 1.3 instument. (Kidney Diseases Quality of Life Short Form version 1.3)[1 year<br>6 months<br>3 months];Hand grip strength measured using a Smedley hand dynanometer (Sportstek, Victoria, Australia). Subjects will attempt 3 maximal contrations on each side, in a seated position with the arm hanging by the side and the forearm flexed to 90 degrees and the writst in neutral postition. The best recorded force on each side will be recorded as well s the presence of a current arteriovenous fistula or loop and the handedness of the subject.[1 year<br>6 months<br>3 months]