Binocular Visual Therapy and Video Games for Amblyopia Treatment.
- Conditions
- Amblyopia
- Interventions
- Device: Red/green glassesDevice: Electronic TabletDevice: Eye patch
- Registration Number
- NCT03655912
- Lead Sponsor
- Universidad Autonoma de Nuevo Leon
- Brief Summary
Amblyopia, or lazy eye, is best defined by the American Academy of Ophthalmology as a unilateral or bilateral reduction of the best corrected visual acuity that occurs in the setting of an otherwise normal eye, or a structural abnormality involving the eye or visual pathway with reduction in visual acuity that cannot be attributed only to the effect of the structural abnormality. Which causes an abnormal visual experience early in life, with consequences such as deficiencies in the ability to perceive contrast and/or movement, visual acuity, accommodation and stereopsis. The treatment of choice consists in patching of the fellow eye 2 hours per day. The disadvantage of this treatment modality is that patients end up not complying and when treatment is interrupted, lazy eye reappears. Amblyopia was thought to be a monocular disease, now a days there are reports of cortical visual paths changes in both eyes (the fellow and amblyopia eye), believing that it might be a monocular consequence of a binocular disease. Following that statement new treatment studies have arisen, stimulating both eyes not only to improve visual acuity in the lazy eye, but to restore binocular function as well. These treatments use videogames in celular phones, computers, or tablets where the fellow eye is exposed to reduced contrast and the lazy eye is exposed to full-contrast. Although the evidence is promising, more studies are needed to establish effectivity and security of this treatment modality.
- Detailed Description
The objective of this study is to determine if the binocular visual therapy with red-green glasses and the use of electronic devices is effective for amblyopia treatment in children.
Participants will be randomly assigned to one of three treatment modalities: Group A: eye patch on the fellow eye and to near-vision activities (such as reading, drawing, etc) Group B: an eye patch on the fellow eye and a electronic tablet Group C: red/green glasses and a electronic tablet
Treatment will be done buy the three groups daily during 2 consecutive hours, and will be completed for four months. Children will then suspend the therapy for 2 months, and will be reevaluated to determine lazy eye relapses . All groups will be compared to see which patients achieved greater improvement on visual acuity and depth perception.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
- Patients with anisometropic amblyopia, strabismic amblyopia or both
- Patients with out previous amblyopia treatment
- Patient with previous strabismus surgery or use of there best corrected visual acuity glasses for at least 1 month
- Birth at term gestational age
- Without any systemic or ophthalmic comorbidities
- Previous patients parent verbal and fiscal assessment.
- Any other amblyopia diagnosis (deprivation)
- Any previous amblyopia treatment
- Any previous intraocular surgery
- Any ocular condition
- Any neurologic conditions or psychomotor development alterations
- Patients not able to cooperate for visual acuity or stereopsis evaluation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Red/Green Glasses Red/green glasses Red/green glasses and a electronic tablet Electronic Devices Electronic Tablet Eye patch on the fellow eye and a electronic tablet Patch Eye patch Eye patch on the fellow eye and to near-vision activities (such as reading, drawing, etc)
- Primary Outcome Measures
Name Time Method Best corrected visual acuity of the amblyopic eye Four months of treatment Best corrected visual acuity of the amblyopic eye using the Snellen chart. Measurements will be converted to LogMar values for statistical analysis.
Best corrected visual acuity of the amblyopic eye two months after treatment suspension to determine lazy eye relapses Two months after treatment suspension. Best corrected visual acuity of the amblyopic eye using the Snellen chart. Measurements will be converted to LogMar values for statistical analysis.
- Secondary Outcome Measures
Name Time Method Stereopsis two months after treatment suspension to determine lazy eye relapses Two months after treatment suspension. Stereopsis measurement by titmus test
Stereopsis Four months of treatment Stereopsis measurement by titmus test
Trial Locations
- Locations (1)
Departamento de Oftalmologia, Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
🇲🇽Monterrey, Nuevo Leon, Mexico