Skip to main content
Clinical Trials/NCT03423888
NCT03423888
Completed
Not Applicable

Acceptability of High-flow Nasal Oxygen to Relieve Dyspnea in Palliative Care: Pilot Study

University Hospital, Toulouse1 site in 1 country30 target enrollmentFebruary 13, 2018
ConditionsDyspnea

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Dyspnea
Sponsor
University Hospital, Toulouse
Enrollment
30
Locations
1
Primary Endpoint
Acceptability of HNFC in patients with dyspnea in palliative care during one week
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

In palliative care, the relief of the dyspnea is necessary. Medications for the reduction of dyspnea have side effects. High-flow nasal cannula oxygen therapy (HFNC) is a new way to deliver oxygen. Investigators hypothesize that HNFC is an acceptable technic for the patient with dyspnea in palliative care.

A pilot study with 30 patients will be conducted. Acceptability of HNFC will be studied by the time of use by patients of the HNFC during one week. The effectiveness of HNFC in relieving dyspnea will be studied using Borg scale.

Detailed Description

Pilot study for acceptability of high flow nasal cannula oxygen therapy in palliative care Population: 30 patients in palliative care (for lung cancer, terminal respiratory failure) who suffer from dyspnea and have oxygen therapy. Patients with curative care are excluded and patients who require non invasive ventilation. An oral consent is asked. Primary objective: acceptability of HNFC in patients with dyspnea in palliative care during one week Secondary objectives: * Tolerance of HNFC at short term (1h and 24h) and long term (7 days) after initiation of HNFC * Efficiency of HNFC at short term Primary outcome: duration of use of the HNFC during 7 days Secondary outcome: * Tolerance: noise of the system of HNFC, side effects of high flow (nasal dryness..) * Efficiency: evaluation of dyspnea by Borg scale and measure of respiratory rate and saturation of oxygen one hour after initiation of HNFC

Registry
clinicaltrials.gov
Start Date
February 13, 2018
End Date
January 25, 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient followed for respiratory failure with palliative care and :
  • More than 18 years old
  • Dyspnea related to a respiratory disease
  • Hypoxemia requiring the introduction of more than 4 liters of oxygen for a sp02 \> 90%
  • Patient affiliated to a social security system

Exclusion Criteria

  • Patient less than 18 years old
  • Patient with guardianship, trusteeship
  • No consent for participation at the study
  • Project of curative care

Outcomes

Primary Outcomes

Acceptability of HNFC in patients with dyspnea in palliative care during one week

Time Frame: 7 days

Duration of use of HNFC: nurses will set up the device to the patient who can withdraw it at any time. It will then be noted the stop time and recovery of the device for a week, which will know the time of use and acceptability. If the patient wishes to permanently stop the use of the device, the stop time will be raised.

Secondary Outcomes

  • Efficiency of high-flow nasal oxygen in palliative care with Sp02(At short term: one hour after the initiation and at long term: 24h and seven days after the start)
  • Efficiency of high-flow nasal oxygen in palliative care with respiratory rate(At short term: one hour after the initiation and at long term: 24h and seven days after the start)
  • Efficiency of high-flow nasal oxygen in palliative care with dyspnea(At short term: one hour after the initiation and at long term: 24h and seven days after the start)

Study Sites (1)

Loading locations...

Similar Trials