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Effects of Rhus coriaria L. fruits on lipid profile,Apolipoprotein A , B and Inflammatory factor (hs-CRP) in dyslipidemia patients

Phase 2
Conditions
Condition 1: Pure hypercholesterolaemia. Condition 2: Hyperlipidaemia, unspecified. Condition 3: Other disorders of lipoprotein metabolism. Condition 4: Blood pressure. Condition 5: flow-mediated dilatation (FMD).
Pure hypercholesterolaemia
Hyperlipidaemia, unspecified
Other disorders of lipoprotein metabolism
Hypertensive diseases
Diseases of arteries, arterioles and capillaries
I10-I15
I70-I79
Registration Number
IRCT201505309662N9
Lead Sponsor
Vice Chancellor for research of Isfahan University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
30
Inclusion Criteria

Inclusion criteria : in dyslipidemic patients; subjects aged 35–70 years ; over 5/18 mM cholesterol (200 mg per deciliter); over 3/ 37mM LDL (130 mg dL).

exclusion criteria : Individuals with a history of diseases; diabetes; cardiovascular disease; liver and kidney as well as pregnant and breastfeeding; supplements like fish oil which is affect on blood lipids levels; the use of immunosuppressive drugs

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
HDL. Timepoint: Before and after 4 weeks. Method of measurement: Parss Azmon KIT/Device Hitachi.;LDL. Timepoint: Before and after 4 weeks. Method of measurement: Parss Azmon KIT/Device Hitachi.;Total cholestrol. Timepoint: Before and after 4 weeks. Method of measurement: Parss Azmon KIT/Device Hitachi.;TG. Timepoint: Before and after 4 weeks. Method of measurement: Parss Azmon KIT/Device Hitachi.;Blood pressure. Timepoint: Before and after 4 weeks. Method of measurement: Sphygmomanometer.;Endothelial Function. Timepoint: Before and after 4 weeks. Method of measurement: Doppler ultrasonography.
Secondary Outcome Measures
NameTimeMethod
Inflammatory markers. Timepoint: Before and after 4 weeks. Method of measurement: ELISA Kit.;Weight. Timepoint: Before and after 4 weeks. Method of measurement: scale.
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