S1403, Afatinib Dimaleate With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage IV or Recurrent, EGFR Mutation Positive Non-small Cell Lung Cancer

Phase 2

Active, not recruiting

Conditions: Stage IV Non-Small Cell Lung Cancer
Recurrent Non-Small Cell Lung Carcinoma

Interventions: Drug: Afatinib Dimaleate
Biological: Cetuximab
Other: Laboratory Biomarker Analysis

Registration Number: NCT02438722

Lead Sponsor: SWOG Cancer Research Network

Brief Summary: This randomized phase II/III trial studies how well afatinib dimaleate with cetuximab works and compares it with afatinib dimaleate alone in treating patients with newly diagnosed stage IV or recurrent (has come back), epidermal growth factor receptor (EGFR) mutation positive non-small cell lung cancer. Afatinib dimaleate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as cetuximab, may block tumor growth in different ways by targeting certain cells. It is not yet known whether afatinib dimaleate is more effective when given alone or with cetuximab in treating patients with non-small cell lung cancer.

Detailed Description: PRIMARY OBJECTIVES:

I. To evaluate if there is sufficient evidence to continue to the phase III component by comparing progression-free survival (PFS) between patients randomized to afatinib (afatinib dimaleate) in combination with cetuximab versus afatinib alone in the first-line treatment of patients with advanced EGFR-mutant non-small cell lung cancer (NSCLC). (Phase II) II. To determine the efficacy of the combination of afatinib and cetuximab compared to afatinib alone as measured by overall survival (OS) in the first-line treatment of patients with advanced EGFR-mutant NSCLC. (Phase III)

SECONDARY OBJECTIVES:

I. To evaluate the overall response rate (confirmed and unconfirmed, complete and partial responses) in the subset of patients with measurable disease treated with afatinib plus cetuximab compared to afatinib alone.

II. To assess the safety of each treatment arm when used in the first-line setting.

III. To compare time to treatment failure and time to treatment discontinuation between randomized to afatinib in combination with cetuximab versus afatinib alone.

TERTIARY OBJECTIVES:

I. To investigate the molecular mechanisms that confer benefit from afatinib and afatinib plus cetuximab by evaluating whether the presence of de novo EGFR T790M mutation or other molecular alterations in the pre-treatment tumor influence the clinical outcomes.

II. To quantitatively assess whether the ratio of sensitizing EGFR (EGFRs) mutation to EGFR T790M influences outcome and is altered during treatment.

III. To evaluate the frequency of known mechanisms of resistance to EGFR-directed therapies in the context of afatinib plus cetuximab and afatinib alone treatment.

IV. To identify potential novel predictors of benefit to afatinib plus cetuximab.

V. To identify potential new mechanisms of resistance to EGFR-directed therapies.

VI. To establish patient-derived xenografts (PDXs) from a subset of patients by re-biopsy at the time of progressive disease for drug testing and genomic analysis.

VII. To assess whether circulating tumor markers can be used as indicators of sensitivity and resistance to afatinib plus cetuximab and afatinib alone.

VIII. To determine whether the levels of EGFR protein by immunohistochemistry predict for benefit to afatinib plus cetuximab and afatinib alone.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive afatinib dimaleate orally (PO) once daily (QD) on days 1-28 and cetuximab intravenously (IV) over 2 hours on days 1 and 15. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM II: Patients receive afatinib dimaleate as in Arm I. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up for 3 years.

Recruitment & Eligibility

Status: ACTIVE_NOT_RECRUITING

Sex: All

Target Recruitment: 174

Inclusion Criteria

Patients must have histologically or cytologically confirmed stage IV (American Joint Committee on Cancer [AJCC] 7th Edition) or recurrent non-small cell lung cancer (NSCLC)
Patients must have documented presence of an EGFR exon 19 deltion or exon 21 (L858R) substitution mutation; T790M mutation or other molecular abnormality will be allowed as long as it accompanies one of the mutations listed above; EGFR testing must be performed using a Food and Drug Administration (FDA)-approved test or in a Clinical Laboratory Improvement Amendments (CLIA)-certified laboratory.
Patients must have tissue available and must agree to submission of tissue and blood; one to two paraffin-embedded tissue blocks or 15-20 unstained slides are requested (a minimum of 12 slides is required); cytology (i.e. fine-needle aspirations, pleural effusion specimens) is acceptable if a cell block or sufficient unstained slides are available; tumor material must be reviewed by a local pathologist who must confirm that at least 100 viable tumor cells are present in the sample and sign the S1403 Pathology Review Form; patients must also be willing to submit blood samples for correlative research at baseline, during treatment and at progression
Patients enrolled at sites participating in the Repeat Biopsy Study must agree to submission of tissue obtained by a repeat biopsy performed at the time of disease progression
Patients must not have received any prior systemic anticancer therapy for advanced or metastatic disease including chemotherapy or EGFR tyrosine kinase inhibitor therapy (including gefitinib, erlotinib, afatinib, or any experimental EGFR tyrosine kinase inhibitors [TKI] agents); prior chemotherapy for non-metastatic disease (i.e. adjuvant therapy or concurrent chemo-radiotherapy) is allowed as long as > 12 months has passed since completion of therapy; adjuvant EGFR-directed therapy is not allowed; local therapy (i.e. palliative radiotherapy) is allowed as long as a period of 7 days has passed since the last dose was received and the patient has recovered from any associated toxicity at the time of registration
Patients may have measurable or non-measurable disease documented by computed tomography (CT) or magnetic resonance imaging (MRI) within 42 days prior to registration; the CT from a combined positron emission tomography (PET)/CT may be used only if it is of diagnostic quality; laboratory parameters are not acceptable as the only evidence of disease; in order to qualify as measurable, measurable disease must be outside previous radiation field; all disease must be assessed and documented on the Baseline Tumor Assessment Form (Response Evaluation Criteria in Solid Tumors [RECIST] 1.1)
Patients must have a CT or MRI scan of the brain to evaluate for central nervous system (CNS) disease within 42 days prior to registration; patient must not have symptomatic brain metastases or evidence of leptomeningeal carcinomatosis; patients with asymptomatic brain metastases are eligible if off of steroids for at least 7 days prior to registration without development of symptoms
Patients must not have any known clinically active interstitial lung disease
Absolute neutrophil count (ANC) >= 1,500/mcL
Platelets >= 75,000/mcL
Hemoglobin >= 9 g/dL
Total bilirubin =< 1.5 x institutional upper limit of normal (IULN)
Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) =< 2.5 x IULN (or =< 5 x IULN for patients with known liver metastases)
Serum creatinine =< 1.5 x IULN OR measured or calculated creatinine clearance >= 60 mL/min
Patients must not have significant gastrointestinal disorders with diarrhea as a major symptom (e.g. Crohn's disease, malabsorption, etc)
Patients must be able to swallow medication by oral route
Patients must not have a history of clinically relevant cardiovascular abnormalities such as uncontrolled hypertension, congestive heart failure New York Heart Association (NYHA) classification of 3, unstable angina or poorly controlled arrhythmia or myocardial infarction within 6 months prior to registration; if clinically indicated, echocardiogram or multigated acquisition (MUGA) must be performed and cardiac ejection fraction must be >= 50%
Patients must not have had major surgery within 28 days prior to registration or be scheduled for surgery during the projected course of protocol treatment; tumor biopsy is allowed
Patients must not have a known history of active hepatitis B infection (defined as presence of hepatitis B surface antigen [Hep B sAg] and/ or Hep B deoxyribonucleic acid [DNA]), active hepatitis C infection (defined as presence of hepatitis C [Hep C] ribonucleic acid [RNA]) and/or known human immunodeficiency virus (HIV) seropositive
Patients must not have any other concomitant serious illness or organ system dysfunction which in the opinion of the investigator would either compromise patient safety or interfere with the evaluation of the safety of the study drug
Patients must not be planning to receive any other investigational agents during the course of protocol treatment
Patients must not have a history of allergic reactions attributed to compounds of similar chemical or biologic composition to afatinib and/or cetuximab
Prestudy history and physical must be obtained with 28 days prior to registration
Patients must have Zubrod performance status of 0 - 2
No other prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease free for three years
Patients must not be pregnant or nursing; women/men of reproductive potential must have agreed to use an effective contraceptive method; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures
Patients must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines
As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

Exclusion Criteria

Not provided

Study & Design

Study Type: INTERVENTIONAL

Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Arm II (afatinib dimaleate)	Afatinib Dimaleate	Patients receive afatinib dimaleate as in Arm I. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Arm I (afatinib dimaleate, cetuximab)	Cetuximab	Patients receive afatinib dimaleate PO QD on days 1-28 and cetuximab IV over 2 hours on days 1 and 15. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Arm II (afatinib dimaleate)	Laboratory Biomarker Analysis	Patients receive afatinib dimaleate as in Arm I. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Arm I (afatinib dimaleate, cetuximab)	Afatinib Dimaleate	Patients receive afatinib dimaleate PO QD on days 1-28 and cetuximab IV over 2 hours on days 1 and 15. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Arm I (afatinib dimaleate, cetuximab)	Laboratory Biomarker Analysis	Patients receive afatinib dimaleate PO QD on days 1-28 and cetuximab IV over 2 hours on days 1 and 15. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

Primary Outcome Measures

Name	Time	Method
2-year Overall Survival Rate	Up to 3 years post registration	Percentage of participants still alive 2 years post registration. KM estimate at 2 years is presented, Overall Survival assessed for a total of 3 years in order to calculate value.
Progression-Free Survival	up to 3 years post registration	From date of registration to date of first documentation of progression or symptomatic deterioration or death due to any cause. Progression is defined using Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.1), as a 20% increase in the sum of appropriate diameters of target measurable lesions over smallest sum observed, as well as an absolute increase of at least 0.5 cm. Unequivocal progression of non-measurable disease in the opinion of treating physician. Appearance of any new lesion/site. Death due to disease without prior documentation of progression and without symptomatic deterioration.

Secondary Outcome Measures

Name	Time	Method
Number of Patients With Gr 3 Through 5 Adverse Events That Are Related to Study Drugs	Duration of treatment and follow up until death or 3 years post registration	Routine Adverse Events are reported by CTCAE4.0. For serious adverse event reporting, we updated from CTCAE4.0 to CTCAE5.0. . Only adverse events that are possibly, probably or definitely related to study drug are reported.
Response Rates	Up to 3 years	Percentage of participants with confirmed and unconfirmed, partial response and complete response to treatment Response Evaluation Criteria in Solid Tumors Criteria (RECIST 1.1). Per Response Evaluation Criteria In Solid Tumors Criteria (RECIST v1.1) for target lesions: Complete Response (CR), Disappearance of all target lesions; Partial Response (PR), \>=30% decrease in the sum of appropriate diameters of all target measurable lesions; Overall Response (OR) = CR + PR.
Time to Treatment Discontinuation	up to 3 years post-registration	From date of registration to date of discontinuation of treatment or death due to any cause
Time to Treatment Failure	assessed up to 3 years post registration	From date of registration to date of first documentation of progression or symptomatic deterioration, early discontinuation of treatment, or death due to any cause.

Trial Locations

Locations (634): Onslow Memorial Hospital
🇺🇸
Jacksonville, North Carolina, United States
Boston Baskin Cancer Center-Bartlett
🇺🇸
Bartlett, Tennessee, United States
The Carle Foundation Hospital
🇺🇸
Urbana, Illinois, United States
UC San Diego Moores Cancer Center
🇺🇸
La Jolla, California, United States
Palo Alto Medical Foundation-Camino Division
🇺🇸
Mountain View, California, United States
Mercy Hospital Fort Smith
🇺🇸
Fort Smith, Arkansas, United States
Sutter Auburn Faith Hospital
🇺🇸
Auburn, California, United States
Sutter Cancer Research Consortium
🇺🇸
Novato, California, United States
Kaiser Permanente-Baldwin Park
🇺🇸
Baldwin Park, California, United States
CHI Saint Vincent Cancer Center Hot Springs
🇺🇸
Hot Springs, Arkansas, United States
Palo Alto Medical Foundation-Fremont
🇺🇸
Fremont, California, United States
Sutter Cancer Centers Radiation Oncology Services-Auburn
🇺🇸
Auburn, California, United States
AIS Cancer Center at San Joaquin Community Hospital
🇺🇸
Bakersfield, California, United States
Kaiser Permanente-Irvine
🇺🇸
Irvine, California, United States
Mercy UC Davis Cancer Center
🇺🇸
Merced, California, United States
Alta Bates Summit Medical Center-Herrick Campus
🇺🇸
Berkeley, California, United States
Kaiser Permanente Los Angeles Medical Center
🇺🇸
Los Angeles, California, United States
PCR Oncology
🇺🇸
Arroyo Grande, California, United States
Sutter Davis Hospital
🇺🇸
Davis, California, United States
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
🇺🇸
Cameron Park, California, United States
Memorial Medical Center
🇺🇸
Springfield, Illinois, United States
Kaiser Permanente-Fontana
🇺🇸
Fontana, California, United States
Kaiser Permanente - Harbor City
🇺🇸
Harbor City, California, United States
Palo Alto Medical Foundation-Gynecologic Oncology
🇺🇸
Mountain View, California, United States
Mills-Peninsula Medical Center
🇺🇸
Burlingame, California, United States
Idaho Urologic Institute-Meridian
🇺🇸
Meridian, Idaho, United States
Elmhurst Memorial Hospital
🇺🇸
Elmhurst, Illinois, United States
Eden Hospital Medical Center
🇺🇸
Castro Valley, California, United States
Palo Alto Medical Foundation-Sunnyvale
🇺🇸
Sunnyvale, California, United States
Western Illinois Cancer Treatment Center
🇺🇸
Galesburg, Illinois, United States
Penrose-Saint Francis Healthcare
🇺🇸
Colorado Springs, Colorado, United States
Rocky Mountain Cancer Centers-Longmont
🇺🇸
Longmont, Colorado, United States
Smilow Cancer Hospital Care Center-Fairfield
🇺🇸
Fairfield, Connecticut, United States
Rocky Mountain Cancer Centers-Penrose
🇺🇸
Colorado Springs, Colorado, United States
Wilcox Memorial Hospital and Kauai Medical Clinic
🇺🇸
Lihue, Hawaii, United States
The Cancer Center of Hawaii-Pali Momi
🇺🇸
'Aiea, Hawaii, United States
Kootenai Medical Center
🇺🇸
Coeur d'Alene, Idaho, United States
Centralia Oncology Clinic
🇺🇸
Centralia, Illinois, United States
Sutter Pacific Medical Foundation
🇺🇸
Santa Rosa, California, United States
Illinois CancerCare-Pekin
🇺🇸
Pekin, Illinois, United States
Carle Physician Group-Effingham
🇺🇸
Effingham, Illinois, United States
Edward Hospital/Cancer Center
🇺🇸
Naperville, Illinois, United States
Kaiser Permanente-San Marcos
🇺🇸
San Marcos, California, United States
Trinity Medical Center
🇺🇸
Moline, Illinois, United States
Saint Alphonsus Medical Center-Nampa
🇺🇸
Nampa, Idaho, United States
Pali Momi Medical Center
🇺🇸
'Aiea, Hawaii, United States
Saint Alphonsus Cancer Care Center-Caldwell
🇺🇸
Caldwell, Idaho, United States
Kootenai Cancer Center
🇺🇸
Post Falls, Idaho, United States
Delaware Clinical and Laboratory Physicians PA
🇺🇸
Newark, Delaware, United States
Saint Alphonsus Cancer Care Center-Boise
🇺🇸
Boise, Idaho, United States
Beebe Medical Center
🇺🇸
Lewes, Delaware, United States
Illinois CancerCare-Carthage
🇺🇸
Carthage, Illinois, United States
Smilow Cancer Hospital-Orange Care Center
🇺🇸
Orange, Connecticut, United States
Walter Knox Memorial Hospital
🇺🇸
Emmett, Idaho, United States
Smilow Cancer Hospital Care Center-Trumbull
🇺🇸
Trumbull, Connecticut, United States
Smilow Cancer Hospital-Derby Care Center
🇺🇸
Derby, Connecticut, United States
Rocky Mountain Cancer Centers - Pueblo
🇺🇸
Pueblo, Colorado, United States
Saint Joseph Medical Center
🇺🇸
Bloomington, Illinois, United States
Illinois CancerCare-Bloomington
🇺🇸
Bloomington, Illinois, United States
Radiation Oncology of Northern Illinois
🇺🇸
Ottawa, Illinois, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
🇺🇸
Savannah, Georgia, United States
Spector, David MD (UIA Investigator)
🇺🇸
Moline, Illinois, United States
Reid Health
🇺🇸
Richmond, Indiana, United States
Kootenai Cancer Clinic
🇺🇸
Sandpoint, Idaho, United States
Rush - Copley Medical Center
🇺🇸
Aurora, Illinois, United States
Decatur Memorial Hospital
🇺🇸
Decatur, Illinois, United States
Illinois CancerCare-Canton
🇺🇸
Canton, Illinois, United States
Mary Greeley Medical Center
🇺🇸
Ames, Iowa, United States
Crossroads Cancer Center
🇺🇸
Effingham, Illinois, United States
Illinois CancerCare-Eureka
🇺🇸
Eureka, Illinois, United States
Illinois CancerCare-Kewanee Clinic
🇺🇸
Kewanee, Illinois, United States
Memorial Hospital of Carbondale
🇺🇸
Carbondale, Illinois, United States
SIH Cancer Institute
🇺🇸
Carterville, Illinois, United States
Illinois CancerCare-Galesburg
🇺🇸
Galesburg, Illinois, United States
Carle on Vermilion
🇺🇸
Danville, Illinois, United States
Alegent Health Mercy Hospital
🇺🇸
Council Bluffs, Iowa, United States
Good Samaritan Regional Health Center
🇺🇸
Mount Vernon, Illinois, United States
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
🇺🇸
Pekin, Illinois, United States
Woodland Cancer Care Center
🇺🇸
Michigan City, Indiana, United States
Constantinou, Costas L MD (UIA Investigator)
🇺🇸
Bettendorf, Iowa, United States
Cancer Center of Kansas - Fort Scott
🇺🇸
Fort Scott, Kansas, United States
Commonwealth Cancer Center-Corbin
🇺🇸
Corbin, Kentucky, United States
Mercy Hospital Joplin
🇺🇸
Joplin, Missouri, United States
Hematology Oncology Consultants-Clarkston
🇺🇸
Clarkston, Michigan, United States
Cancer Center of Kansas - El Dorado
🇺🇸
El Dorado, Kansas, United States
Chancellor Center for Oncology
🇺🇸
Newburgh, Indiana, United States
McFarland Clinic PC-Trinity Cancer Center
🇺🇸
Fort Dodge, Iowa, United States
Medical Oncology and Hematology Associates-West Des Moines
🇺🇸
Clive, Iowa, United States
Mercy Cancer Center-West Lakes
🇺🇸
Clive, Iowa, United States
Greater Regional Medical Center
🇺🇸
Creston, Iowa, United States
McFarland Clinic PC-Jefferson
🇺🇸
Jefferson, Iowa, United States
IHA Hematology Oncology Consultants-Canton
🇺🇸
Canton, Michigan, United States
Beaumont Hospital-Dearborn
🇺🇸
Dearborn, Michigan, United States
Caro Cancer Center
🇺🇸
Caro, Michigan, United States
Eastern Maine Medical Center
🇺🇸
Bangor, Maine, United States
Minimally Invasive Surgery Hospital
🇺🇸
Lenexa, Kansas, United States
Bronson Battle Creek
🇺🇸
Battle Creek, Michigan, United States
Lahey Hospital and Medical Center
🇺🇸
Burlington, Massachusetts, United States
Flaget Memorial Hospital
🇺🇸
Bardstown, Kentucky, United States
Saint Joseph Mercy Brighton
🇺🇸
Brighton, Michigan, United States
Jewish Hospital Medical Center South
🇺🇸
Shepherdsville, Kentucky, United States
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
🇺🇸
Grosse Pointe Woods, Michigan, United States
IHA Hematology Oncology Consultants-Chelsea
🇺🇸
Chelsea, Michigan, United States
Oncology Hematology Care Inc-Crestview
🇺🇸
Crestview Hills, Kentucky, United States
Borgess Medical Center
🇺🇸
Kalamazoo, Michigan, United States
West Michigan Cancer Center
🇺🇸
Kalamazoo, Michigan, United States
Central Care Cancer Center - Bolivar
🇺🇸
Bolivar, Missouri, United States
Fairview-Southdale Hospital
🇺🇸
Edina, Minnesota, United States
Newland Medical Associates-Clarkston
🇺🇸
Clarkston, Michigan, United States
Monroe Cancer Center
🇺🇸
Monroe, Michigan, United States
Mercy Health Mercy Campus
🇺🇸
Muskegon, Michigan, United States
New Ulm Medical Center
🇺🇸
New Ulm, Minnesota, United States
Harold Alfond Center for Cancer Care
🇺🇸
Augusta, Maine, United States
Winchester Hospital
🇺🇸
Winchester, Massachusetts, United States
Fairview Maple Grove Medical Center
🇺🇸
Maple Grove, Minnesota, United States
Cox Cancer Center Branson
🇺🇸
Branson, Missouri, United States
Minnesota Oncology Hematology PA-Maplewood
🇺🇸
Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast
🇺🇸
Maplewood, Minnesota, United States
Genesee Cancer and Blood Disease Treatment Center
🇺🇸
Flint, Michigan, United States
Southeast Cancer Center
🇺🇸
Cape Girardeau, Missouri, United States
Hope Cancer Clinic
🇺🇸
Livonia, Michigan, United States
Lake Huron Medical Center
🇺🇸
Port Huron, Michigan, United States
Genesys Hurley Cancer Institute
🇺🇸
Flint, Michigan, United States
Bronson Methodist Hospital
🇺🇸
Kalamazoo, Michigan, United States
Michigan Breast Specialists-Warren
🇺🇸
Warren, Michigan, United States
Allegiance Health
🇺🇸
Jackson, Michigan, United States
Baptist Memorial Hospital and Cancer Center-Desoto
🇺🇸
Southhaven, Mississippi, United States
Saint Mary's of Michigan
🇺🇸
Saginaw, Michigan, United States
Ridgeview Medical Center
🇺🇸
Waconia, Minnesota, United States
Spectrum Health Reed City Hospital
🇺🇸
Reed City, Michigan, United States
Great Plains Health Callahan Cancer Center
🇺🇸
North Platte, Nebraska, United States
Parkland Health Center-Bonne Terre
🇺🇸
Bonne Terre, Missouri, United States
Heartland Hematology and Oncology
🇺🇸
Kearney, Nebraska, United States
Bhadresh Nayak MD PC-Warren
🇺🇸
Warren, Michigan, United States
Nebraska Cancer Research Center
🇺🇸
Lincoln, Nebraska, United States
Sanford Clinic North-Bemidgi
🇺🇸
Bemidji, Minnesota, United States
Las Vegas Cancer Center-Henderson
🇺🇸
Henderson, Nevada, United States
Carson Tahoe Regional Medical Center
🇺🇸
Carson City, Nevada, United States
Comprehensive Cancer Centers of Nevada-Southeast Henderson
🇺🇸
Henderson, Nevada, United States
Munson Medical Center
🇺🇸
Traverse City, Michigan, United States
21st Century Oncology-Henderson
🇺🇸
Henderson, Nevada, United States
Fairview Ridges Hospital
🇺🇸
Burnsville, Minnesota, United States
Unity Hospital
🇺🇸
Fridley, Minnesota, United States
Regions Hospital
🇺🇸
Saint Paul, Minnesota, United States
CHI Health Good Samaritan
🇺🇸
Kearney, Nebraska, United States
Faith Regional Health Services Carson Cancer Center
🇺🇸
Norfolk, Nebraska, United States
Centerpoint Medical Center LLC
🇺🇸
Independence, Missouri, United States
Capital Region Medical Center-Goldschmidt Cancer Center
🇺🇸
Jefferson City, Missouri, United States
Southeast Nebraska Cancer Center
🇺🇸
Lincoln, Nebraska, United States
Comprehensive Cancer Centers of Nevada - Henderson
🇺🇸
Henderson, Nevada, United States
Renown Regional Medical Center
🇺🇸
Reno, Nevada, United States
Inspira Medical Center Woodbury
🇺🇸
Woodbury, New Jersey, United States
Sanford Clinic North-Fargo
🇺🇸
Fargo, North Dakota, United States
Southeastern Medical Oncology Center-Goldsboro
🇺🇸
Goldsboro, North Carolina, United States
Cancer Care of Western North Carolina
🇺🇸
Asheville, North Carolina, United States
Delbert Day Cancer Institute at PCRMC
🇺🇸
Rolla, Missouri, United States
Dayton Physicians LLC-Miami Valley South
🇺🇸
Centerville, Ohio, United States
Sainte Genevieve County Memorial Hospital
🇺🇸
Sainte Genevieve, Missouri, United States
Newark Radiation Oncology
🇺🇸
Newark, Ohio, United States
Midlands Community Hospital
🇺🇸
Papillion, Nebraska, United States
Licking Memorial Hospital
🇺🇸
Newark, Ohio, United States
The Toledo Hospital/Toledo Children's Hospital
🇺🇸
Toledo, Ohio, United States
Norris Cotton Cancer Center-Nashua
🇺🇸
Nashua, New Hampshire, United States
Blanchard Valley Hospital
🇺🇸
Findlay, Ohio, United States
Inspira Medical Center Vineland
🇺🇸
Vineland, New Jersey, United States
Christus Saint Vincent Regional Cancer Center
🇺🇸
Santa Fe, New Mexico, United States
Akron General Medical Center
🇺🇸
Akron, Ohio, United States
Southeastern Medical Oncology Center-Clinton
🇺🇸
Clinton, North Carolina, United States
Miami Valley Hospital South
🇺🇸
Centerville, Ohio, United States
Asheville Hematology-Oncology Associates
🇺🇸
Asheville, North Carolina, United States
Greater Dayton Cancer Center
🇺🇸
Kettering, Ohio, United States
Armes Family Cancer Center
🇺🇸
Findlay, Ohio, United States
Norris Cotton Cancer Center-Manchester
🇺🇸
Manchester, New Hampshire, United States
Dartmouth Hitchcock Medical Center
🇺🇸
Lebanon, New Hampshire, United States
Dayton Physicians LLC-Wayne
🇺🇸
Greenville, Ohio, United States
Memorial Medical Center - Las Cruces
🇺🇸
Las Cruces, New Mexico, United States
Wayne Hospital
🇺🇸
Greenville, Ohio, United States
Strecker Cancer Center-Belpre
🇺🇸
Belpre, Ohio, United States
Dayton Physicians LLC-Upper Valley
🇺🇸
Troy, Ohio, United States
Sanford Broadway Medical Center
🇺🇸
Fargo, North Dakota, United States
Lehigh Valley Hospital - Muhlenberg
🇺🇸
Bethlehem, Pennsylvania, United States
Wayne Radiation Oncology
🇺🇸
Goldsboro, North Carolina, United States
Springfield Regional Medical Center
🇺🇸
Springfield, Ohio, United States
Park Ridge Hospital Breast Health Center
🇺🇸
Hendersonville, North Carolina, United States
Marietta Memorial Hospital
🇺🇸
Marietta, Ohio, United States
Springfield Regional Cancer Center
🇺🇸
Springfield, Ohio, United States
Dayton Physicians LLC-Atrium
🇺🇸
Franklin, Ohio, United States
Fairfield Medical Center
🇺🇸
Lancaster, Ohio, United States
Christiana Care Health System-Concord Health Center
🇺🇸
Chadds Ford, Pennsylvania, United States
Southern Ohio Medical Center
🇺🇸
Portsmouth, Ohio, United States
UPMC-Coraopolis/Heritage Valley Radiation Oncology
🇺🇸
Moon, Pennsylvania, United States
Mission Hospital-Memorial Campus
🇺🇸
Asheville, North Carolina, United States
Sampson Radiation Oncology
🇺🇸
Clinton, North Carolina, United States
UPMC Cancer Center at UPMC McKeesport
🇺🇸
McKeesport, Pennsylvania, United States
Trinity Cancer Care Center
🇺🇸
Minot, North Dakota, United States
Saint Alphonsus Medical Center-Ontario
🇺🇸
Ontario, Oregon, United States
UPMC Cancer Centers - Arnold Palmer Pavilion
🇺🇸
Greensburg, Pennsylvania, United States
Atrium Medical Center-Middletown Regional Hospital
🇺🇸
Franklin, Ohio, United States
Harrison HealthPartners Hematology and Oncology-Bremerton
🇺🇸
Bremerton, Washington, United States
Adams Cancer Center
🇺🇸
Gettysburg, Pennsylvania, United States
Baptist Memorial Hospital for Women
🇺🇸
Memphis, Tennessee, United States
Family Cancer Center-Memphis
🇺🇸
Memphis, Tennessee, United States
Saint Francis Cancer Center
🇺🇸
Greenville, South Carolina, United States
Flower Hospital
🇺🇸
Sylvania, Ohio, United States
Integrity Oncology PLLC-Collierville
🇺🇸
Collierville, Tennessee, United States
Genesis Healthcare System Cancer Care Center
🇺🇸
Zanesville, Ohio, United States
Knox Community Hospital
🇺🇸
Mount Vernon, Ohio, United States
Saint Alphonsus Medical Center-Baker City
🇺🇸
Baker City, Oregon, United States
Rogue Valley Medical Center
🇺🇸
Medford, Oregon, United States
Highline Medical Center-Main Campus
🇺🇸
Burien, Washington, United States
Guthrie Medical Group PC-Robert Packer Hospital
🇺🇸
Sayre, Pennsylvania, United States
Three Rivers Community Hospital
🇺🇸
Grants Pass, Oregon, United States
UPMC-Johnstown/John P. Murtha Regional Cancer Center
🇺🇸
Johnstown, Pennsylvania, United States
UPMC Susquehanna
🇺🇸
Williamsport, Pennsylvania, United States
WellSpan Health-York Cancer Center
🇺🇸
York, Pennsylvania, United States
Temple University Hospital
🇺🇸
Philadelphia, Pennsylvania, United States
Greenville Health System Cancer Institute-Spartanburg
🇺🇸
Spartanburg, South Carolina, United States
Aurora Health Care Germantown Health Center
🇺🇸
Germantown, Wisconsin, United States
Sanford Cancer Center Oncology Clinic
🇺🇸
Sioux Falls, South Dakota, United States
Pulmonary Medicine Center of Chattanooga-Hixson
🇺🇸
Hixson, Tennessee, United States
Memorial GYN Plus
🇺🇸
Ooltewah, Tennessee, United States
Greenville Health System Cancer Institute-Greer
🇺🇸
Greer, South Carolina, United States
UPMC-Heritage Valley Health System Beaver
🇺🇸
Beaver, Pennsylvania, United States
Aurora Health Center-Fond du Lac
🇺🇸
Fond Du Lac, Wisconsin, United States
Marshfield Clinic Cancer Center - Eau Claire
🇺🇸
Eau Claire, Wisconsin, United States
Harrison Medical Center
🇺🇸
Bremerton, Washington, United States
WellSpan Health-York Hospital
🇺🇸
York, Pennsylvania, United States
Vanderbilt-Ingram Cancer Center Cool Springs
🇺🇸
Franklin, Tennessee, United States
Greenville Health System Cancer Institute-Easley
🇺🇸
Easley, South Carolina, United States
Chester County Hospital
🇺🇸
West Chester, Pennsylvania, United States
Langlade Hospital and Cancer Center
🇺🇸
Antigo, Wisconsin, United States
Diagnostic and Treatment Center
🇺🇸
Weston, Wisconsin, United States
Sanford USD Medical Center - Sioux Falls
🇺🇸
Sioux Falls, South Dakota, United States
Aurora Cancer Care-Kenosha South
🇺🇸
Kenosha, Wisconsin, United States
Marshfield Medical Center
🇺🇸
Marshfield, Wisconsin, United States
Baptist Memorial Hospital and Cancer Center-Memphis
🇺🇸
Memphis, Tennessee, United States
Greenville Health System Cancer Institute-Faris
🇺🇸
Greenville, South Carolina, United States
Vince Lombardi Cancer Clinic-Marinette
🇺🇸
Marinette, Wisconsin, United States
Franciscan Research Center-Northwest Medical Plaza
🇺🇸
Tacoma, Washington, United States
Marshfield Clinic-Chippewa Center
🇺🇸
Chippewa Falls, Wisconsin, United States
Bay Area Medical Center
🇺🇸
Marinette, Wisconsin, United States
Columbia Saint Mary's Hospital - Ozaukee
🇺🇸
Mequon, Wisconsin, United States
Aurora Cancer Care-Racine
🇺🇸
Racine, Wisconsin, United States
Aurora Bay Area Medical Group-Marinette
🇺🇸
Marinette, Wisconsin, United States
Big Horn Basin Cancer Center
🇺🇸
Cody, Wyoming, United States
Marshfield Clinic-Minocqua Center
🇺🇸
Minocqua, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan
🇺🇸
Sheboygan, Wisconsin, United States
Saint Michael's Hospital
🇺🇸
Stevens Point, Wisconsin, United States
Marshfield Clinic - Wisconsin Rapids Center
🇺🇸
Wisconsin Rapids, Wisconsin, United States
University of Pittsburgh Cancer Institute (UPCI)
🇺🇸
Pittsburgh, Pennsylvania, United States
UPMC-Shadyside Hospital
🇺🇸
Pittsburgh, Pennsylvania, United States
UPMC-Passavant Hospital
🇺🇸
Pittsburgh, Pennsylvania, United States
UPMC-Saint Clair Hospital Cancer Center
🇺🇸
Pittsburgh, Pennsylvania, United States
Columbus Oncology and Hematology Associates Inc
🇺🇸
Columbus, Ohio, United States
Riverside Methodist Hospital
🇺🇸
Columbus, Ohio, United States
Grant Medical Center
🇺🇸
Columbus, Ohio, United States
The Mark H Zangmeister Center
🇺🇸
Columbus, Ohio, United States
Doctors Hospital
🇺🇸
Columbus, Ohio, United States
University Medical Center of Southern Nevada
🇺🇸
Las Vegas, Nevada, United States
Cancer and Blood Specialists-Shadow
🇺🇸
Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Central
🇺🇸
Las Vegas, Nevada, United States
University Cancer Center
🇺🇸
Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway
🇺🇸
Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Northwest
🇺🇸
Las Vegas, Nevada, United States
Summerlin Hospital Medical Center
🇺🇸
Las Vegas, Nevada, United States
21st Century Oncology-Fort Apache
🇺🇸
Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada
🇺🇸
Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-San Martin
🇺🇸
Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Southeast
🇺🇸
Las Vegas, Nevada, United States
Cancer Therapy and Integrative Medicine
🇺🇸
Las Vegas, Nevada, United States
21st Century Oncology-Vegas Tenaya
🇺🇸
Las Vegas, Nevada, United States
Cancer and Blood Specialists-Tenaya
🇺🇸
Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Tenaya
🇺🇸
Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Central Valley
🇺🇸
Las Vegas, Nevada, United States
Kaiser Permanente-San Diego Mission
🇺🇸
San Diego, California, United States
Oncology Hematology Care Inc - Anderson
🇺🇸
Cincinnati, Ohio, United States
TriHealth Cancer Institute-Westside
🇺🇸
Cincinnati, Ohio, United States
TriHealth Cancer Institute-Anderson
🇺🇸
Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Eden Park
🇺🇸
Cincinnati, Ohio, United States
Bethesda North Hospital
🇺🇸
Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Kenwood
🇺🇸
Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Blue Ash
🇺🇸
Cincinnati, Ohio, United States
California Pacific Medical Center-Pacific Campus
🇺🇸
San Francisco, California, United States
Abbott-Northwestern Hospital
🇺🇸
Minneapolis, Minnesota, United States
Hennepin County Medical Center
🇺🇸
Minneapolis, Minnesota, United States
Health Partners Inc
🇺🇸
Minneapolis, Minnesota, United States
Dayton Physicians LLC-Wilson
🇺🇸
Sidney, Ohio, United States
Vanderbilt Breast Center at One Hundred Oaks
🇺🇸
Nashville, Tennessee, United States
Vanderbilt University/Ingram Cancer Center
🇺🇸
Nashville, Tennessee, United States
University of Texas Health Science Center at San Antonio
🇺🇸
San Antonio, Texas, United States
Cancer Center of Kansas - Newton
🇺🇸
Newton, Kansas, United States
Cancer Center of Kansas - Salina
🇺🇸
Salina, Kansas, United States
Cancer Center of Kansas - Chanute
🇺🇸
Chanute, Kansas, United States
Kansas Institute of Medicine Cancer and Blood Center
🇺🇸
Lenexa, Kansas, United States
Cancer Center of Kansas - Dodge City
🇺🇸
Dodge City, Kansas, United States
Coffeyville Regional Medical Center
🇺🇸
Coffeyville, Kansas, United States
Cancer Center of Kansas-Independence
🇺🇸
Independence, Kansas, United States
Saint Catherine Hospital
🇺🇸
Garden City, Kansas, United States
Hays Medical Center
🇺🇸
Hays, Kansas, United States
Menorah Medical Center
🇺🇸
Overland Park, Kansas, United States
University of Kansas Cancer Center-Overland Park
🇺🇸
Overland Park, Kansas, United States
Saint Francis Hospital and Medical Center - Topeka
🇺🇸
Topeka, Kansas, United States
Salina Regional Health Center
🇺🇸
Salina, Kansas, United States
Cancer Center of Kansas - Winfield
🇺🇸
Winfield, Kansas, United States
Cancer Center of Kansas - McPherson
🇺🇸
McPherson, Kansas, United States
Saint Rose Ambulatory and Surgery Center
🇺🇸
Great Bend, Kansas, United States
Kansas City NCI Community Oncology Research Program
🇺🇸
Prairie Village, Kansas, United States
Cancer Center of Kansas - Parsons
🇺🇸
Parsons, Kansas, United States
Lawrence Memorial Hospital
🇺🇸
Lawrence, Kansas, United States
University of Kansas Cancer Center-West
🇺🇸
Kansas City, Kansas, United States
University of Kansas Cancer Center
🇺🇸
Kansas City, Kansas, United States
Cancer Center of Kansas - Pratt
🇺🇸
Pratt, Kansas, United States
Billings Clinic-Cody
🇺🇸
Cody, Wyoming, United States
Central Care Cancer Center - Great Bend
🇺🇸
Great Bend, Kansas, United States
Saint Luke's South Hospital
🇺🇸
Overland Park, Kansas, United States
Welch Cancer Center
🇺🇸
Sheridan, Wyoming, United States
Cancer Center of Kansas-Kingman
🇺🇸
Kingman, Kansas, United States
Cancer Center of Kansas-Liberal
🇺🇸
Liberal, Kansas, United States
Cancer Center of Kansas - Wellington
🇺🇸
Wellington, Kansas, United States
Via Christi Hospital-Pittsburg
🇺🇸
Pittsburg, Kansas, United States
Olathe Medical Center
🇺🇸
Olathe, Kansas, United States
Saint Peter's Community Hospital
🇺🇸
Helena, Montana, United States
Saint James Community Hospital and Cancer Treatment Center
🇺🇸
Butte, Montana, United States
Benefis Healthcare- Sletten Cancer Institute
🇺🇸
Great Falls, Montana, United States
Billings Clinic Cancer Center
🇺🇸
Billings, Montana, United States
Bozeman Deaconess Hospital
🇺🇸
Bozeman, Montana, United States
Saint Patrick Hospital - Community Hospital
🇺🇸
Missoula, Montana, United States
Community Medical Hospital
🇺🇸
Missoula, Montana, United States
Saint Vincent Healthcare
🇺🇸
Billings, Montana, United States
Kalispell Regional Medical Center
🇺🇸
Kalispell, Montana, United States
Wayne State University/Karmanos Cancer Institute
🇺🇸
Detroit, Michigan, United States
Saint John Hospital and Medical Center
🇺🇸
Detroit, Michigan, United States
Mercy Hospital Oklahoma City
🇺🇸
Oklahoma City, Oklahoma, United States
Kaiser Permanente Northwest
🇺🇸
Portland, Oregon, United States
Freeman Health System
🇺🇸
Joplin, Missouri, United States
The University of Kansas Cancer Center-Lee's Summit
🇺🇸
Lee's Summit, Missouri, United States
Mercy Clinic-Rolla-Cancer and Hematology
🇺🇸
Rolla, Missouri, United States
Heartland Regional Medical Center
🇺🇸
Saint Joseph, Missouri, United States
Missouri Baptist Medical Center
🇺🇸
Saint Louis, Missouri, United States
Mercy Hospital Springfield
🇺🇸
Springfield, Missouri, United States
CoxHealth South Hospital
🇺🇸
Springfield, Missouri, United States
Altru Cancer Center
🇺🇸
Grand Forks, North Dakota, United States
United Hospital
🇺🇸
Saint Paul, Minnesota, United States
Saint Francis Regional Medical Center
🇺🇸
Shakopee, Minnesota, United States
Lakeview Hospital
🇺🇸
Stillwater, Minnesota, United States
Fairview Lakes Medical Center
🇺🇸
Wyoming, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury
🇺🇸
Woodbury, Minnesota, United States
Eisenhower Medical Center
🇺🇸
Rancho Mirage, California, United States
Kaiser Permanente - Panorama City
🇺🇸
Panorama City, California, United States
Illinois CancerCare-Macomb
🇺🇸
Macomb, Illinois, United States
Illinois CancerCare-Peoria
🇺🇸
Peoria, Illinois, United States
Illinois CancerCare-Ottawa Clinic
🇺🇸
Ottawa, Illinois, United States
Garneau, Stewart C MD (UIA Investigator)
🇺🇸
Moline, Illinois, United States
Loyola University Medical Center
🇺🇸
Maywood, Illinois, United States
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
🇺🇸
Peoria, Illinois, United States
OSF Saint Francis Medical Center
🇺🇸
Peoria, Illinois, United States
Illinois CancerCare-Peru
🇺🇸
Peru, Illinois, United States
Valley Radiation Oncology
🇺🇸
Peru, Illinois, United States
Edward Hospital/Cancer Center?Plainfield
🇺🇸
Plainfield, Illinois, United States
Central Illinois Hematology Oncology Center
🇺🇸
Springfield, Illinois, United States
Springfield Clinic
🇺🇸
Springfield, Illinois, United States
Cancer Care Specialists of Illinois-Swansea
🇺🇸
Swansea, Illinois, United States
Carle Cancer Center
🇺🇸
Urbana, Illinois, United States
Deaconess Clinic Downtown
🇺🇸
Evansville, Indiana, United States
Rush-Copley Healthcare Center
🇺🇸
Yorkville, Illinois, United States
Dayton Physicians LLC-Signal Point
🇺🇸
Middletown, Ohio, United States
Saint Joseph Mercy Chelsea
🇺🇸
Chelsea, Michigan, United States
Genesee Hematology Oncology PC
🇺🇸
Flint, Michigan, United States
Bhadresh Nayak MD PC-Sterling Heights
🇺🇸
Sterling Heights, Michigan, United States
Mercy Health Saint Mary's
🇺🇸
Grand Rapids, Michigan, United States
Saint Mary's Oncology/Hematology Associates of Marlette
🇺🇸
Marlette, Michigan, United States
Great Lakes Cancer Management Specialists-Macomb Medical Campus
🇺🇸
Macomb, Michigan, United States
Michigan Breast Specialists-Macomb Township
🇺🇸
Macomb, Michigan, United States
Weisberg Cancer Treatment Center
🇺🇸
Farmington Hills, Michigan, United States
Saint Mary Mercy Hospital
🇺🇸
Livonia, Michigan, United States
Advanced Breast Care Center PLLC
🇺🇸
Warren, Michigan, United States
Hope Cancer Center
🇺🇸
Pontiac, Michigan, United States
Newland Medical Associates-Pontiac
🇺🇸
Pontiac, Michigan, United States
Marie Yeager Cancer Center
🇺🇸
Saint Joseph, Michigan, United States
IHA Hematology Oncology Consultants-Ann Arbor
🇺🇸
Ypsilanti, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch
🇺🇸
West Branch, Michigan, United States
Parkview Hospital Randallia
🇺🇸
Fort Wayne, Indiana, United States
Saint Luke's East - Lee's Summit
🇺🇸
Lee's Summit, Missouri, United States
Kinston Medical Specialists PA
🇺🇸
Kinston, North Carolina, United States
McFarland Clinic PC-Marshalltown
🇺🇸
Marshalltown, Iowa, United States
McFarland Clinic PC-Boone
🇺🇸
Boone, Iowa, United States
Mercy Medical Center-West Lakes
🇺🇸
West Des Moines, Iowa, United States
Comprehensive Cancer Centers of Nevada-Summerlin
🇺🇸
Las Vegas, Nevada, United States
Las Vegas Cancer Center-Medical Center
🇺🇸
Las Vegas, Nevada, United States
Aurora BayCare Medical Center
🇺🇸
Green Bay, Wisconsin, United States
Marshfield Clinic-Rice Lake Center
🇺🇸
Rice Lake, Wisconsin, United States
Ascension Saint Michael's Hospital
🇺🇸
Stevens Point, Wisconsin, United States
Marshfield Clinic-Wausau Center
🇺🇸
Wausau, Wisconsin, United States
Aurora Medical Center in Summit
🇺🇸
Summit, Wisconsin, United States
Aurora West Allis Medical Center
🇺🇸
West Allis, Wisconsin, United States
Aurora Cancer Care-Milwaukee West
🇺🇸
Wauwatosa, Wisconsin, United States
Marshfield Clinic - Weston Center
🇺🇸
Weston, Wisconsin, United States
Aspirus UW Cancer Center
🇺🇸
Wisconsin Rapids, Wisconsin, United States
Wayne Memorial Hospital
🇺🇸
Goldsboro, North Carolina, United States
Hendersonville Hematology and Oncology at Pardee
🇺🇸
Hendersonville, North Carolina, United States
Margaret R Pardee Memorial Hospital
🇺🇸
Hendersonville, North Carolina, United States
Sutter Medical Center Sacramento
🇺🇸
Sacramento, California, United States
University of California Davis Comprehensive Cancer Center
🇺🇸
Sacramento, California, United States
University of Michigan Comprehensive Cancer Center
🇺🇸
Ann Arbor, Michigan, United States
Alegent Health Immanuel Medical Center
🇺🇸
Omaha, Nebraska, United States
Nebraska Methodist Hospital
🇺🇸
Omaha, Nebraska, United States
Columbia Saint Mary's Water Tower Medical Commons
🇺🇸
Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center
🇺🇸
Milwaukee, Wisconsin, United States
Hematology and Oncology Consultants PC
🇺🇸
Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center
🇺🇸
Omaha, Nebraska, United States
Nebraska Cancer Specialists - Omaha
🇺🇸
Omaha, Nebraska, United States
Oncology Hematology West PC
🇺🇸
Omaha, Nebraska, United States
Alegent Health Lakeside Hospital
🇺🇸
Omaha, Nebraska, United States
Creighton University Medical Center
🇺🇸
Omaha, Nebraska, United States
Aurora Cancer Care-Milwaukee
🇺🇸
Milwaukee, Wisconsin, United States
Aurora Sinai Medical Center
🇺🇸
Milwaukee, Wisconsin, United States
Saint Joseph Mercy Oakland
🇺🇸
Pontiac, Michigan, United States
Saint Joseph Health System-Tawas City
🇺🇸
Tawas City, Michigan, United States
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills
🇺🇸
Las Vegas, Nevada, United States
Carle Physician Group-Mattoon/Charleston
🇺🇸
Mattoon, Illinois, United States
Aurora Cancer Care-Southern Lakes VLCC
🇺🇸
Burlington, Wisconsin, United States
Saint Mary's Regional Medical Center
🇺🇸
Reno, Nevada, United States
McFarland Clinic PC-William R Bliss Cancer Center
🇺🇸
Ames, Iowa, United States
Northwest Medical Specialties PLLC
🇺🇸
Tacoma, Washington, United States
Delaware Radiation Oncology
🇺🇸
Delaware, Ohio, United States
Grady Memorial Hospital
🇺🇸
Delaware, Ohio, United States
Saint Elizabeth Hospital
🇺🇸
Enumclaw, Washington, United States
First Dayton Cancer Care
🇺🇸
Kettering, Ohio, United States
Greenville Health System Cancer Institute-Butternut
🇺🇸
Greenville, South Carolina, United States
Saint Clare Hospital
🇺🇸
Lakewood, Washington, United States
Fowler Family Center for Cancer Care
🇺🇸
Jonesboro, Arkansas, United States
Kaiser Permanente-Anaheim
🇺🇸
Anaheim, California, United States
Kaiser Permanente-Bellflower
🇺🇸
Bellflower, California, United States
Kaiser Permanente-Cadillac
🇺🇸
Los Angeles, California, United States
Fremont - Rideout Cancer Center
🇺🇸
Marysville, California, United States
Palo Alto Medical Foundation Health Care
🇺🇸
Palo Alto, California, United States
Sutter Roseville Medical Center
🇺🇸
Roseville, California, United States
Kaiser Permanente-Riverside
🇺🇸
Riverside, California, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville
🇺🇸
Roseville, California, United States
Kaiser Permanente-San Diego Zion
🇺🇸
San Diego, California, United States
Palo Alto Medical Foundation-Santa Cruz
🇺🇸
Santa Cruz, California, United States
Gene Upshaw Memorial Tahoe Forest Cancer Center
🇺🇸
Truckee, California, United States
Northbay Cancer Center
🇺🇸
Vacaville, California, United States
Sutter Cancer Centers Radiation Oncology Services-Vacaville
🇺🇸
Vacaville, California, United States
Porter Adventist Hospital
🇺🇸
Denver, Colorado, United States
Sutter Solano Medical Center/Cancer Center
🇺🇸
Vallejo, California, United States
Kaiser Permanente-Woodland Hills
🇺🇸
Woodland Hills, California, United States
Mercy Medical Center
🇺🇸
Canton, Ohio, United States
Saint Anthony Hospital
🇺🇸
Lakewood, Colorado, United States
Rocky Mountain Cancer Centers-Lakewood
🇺🇸
Lakewood, Colorado, United States
Southwest Oncology PC
🇺🇸
Durango, Colorado, United States
Mountain Blue Cancer Care Center
🇺🇸
Golden, Colorado, United States
Littleton Adventist Hospital
🇺🇸
Littleton, Colorado, United States
Longmont United Hospital
🇺🇸
Longmont, Colorado, United States
Parker Adventist Hospital
🇺🇸
Parker, Colorado, United States
Rocky Mountain Cancer Centers-Parker
🇺🇸
Parker, Colorado, United States
Saint Mary Corwin Medical Center
🇺🇸
Pueblo, Colorado, United States
Rocky Mountain Cancer Centers-Thornton
🇺🇸
Thornton, Colorado, United States
Yale-New Haven Hospital North Haven Medical Center
🇺🇸
North Haven, Connecticut, United States
Yale-New Haven Shoreline Medical Center
🇺🇸
Guilford, Connecticut, United States
Smilow Cancer Hospital Care Center at Saint Francis
🇺🇸
Hartford, Connecticut, United States
Middlesex Hospital
🇺🇸
Middletown, Connecticut, United States
Smilow Cancer Hospital-Torrington Care Center
🇺🇸
Torrington, Connecticut, United States
Smilow Cancer Hospital-Waterbury Care Center
🇺🇸
Waterbury, Connecticut, United States
Helen F Graham Cancer Center
🇺🇸
Newark, Delaware, United States
Medical Oncology Hematology Consultants PA
🇺🇸
Newark, Delaware, United States
Regional Hematology and Oncology PA
🇺🇸
Newark, Delaware, United States
Christiana Care Health System-Christiana Hospital
🇺🇸
Newark, Delaware, United States
Beebe Health Campus
🇺🇸
Rehoboth Beach, Delaware, United States
Christiana Care Health System-Wilmington Hospital
🇺🇸
Wilmington, Delaware, United States
Sacred Heart Hospital
🇺🇸
Eau Claire, Wisconsin, United States
Nanticoke Memorial Hospital
🇺🇸
Seaford, Delaware, United States
Baptist MD Anderson Cancer Center
🇺🇸
Jacksonville, Florida, United States
Central Georgia Gynecologic Oncology
🇺🇸
Macon, Georgia, United States
Medical Center of Central Georgia
🇺🇸
Macon, Georgia, United States
Memorial University Medical Center
🇺🇸
Savannah, Georgia, United States
Summit Cancer Care-Memorial
🇺🇸
Savannah, Georgia, United States
Low Country Cancer Care Associates PC
🇺🇸
Savannah, Georgia, United States
Summit Cancer Care-Candler
🇺🇸
Savannah, Georgia, United States
South Georgia Medical Center/Pearlman Cancer Center
🇺🇸
Valdosta, Georgia, United States
Hawaii Oncology Inc-Pali Momi
🇺🇸
'Aiea, Hawaii, United States
Cancer Care Specialists of Central Illinois
🇺🇸
Decatur, Illinois, United States
Methodist Medical Center of Illinois
🇺🇸
Peoria, Illinois, United States
Southern Illinois University School of Medicine
🇺🇸
Springfield, Illinois, United States
SwedishAmerican Regional Cancer Center/ACT
🇺🇸
Rockford, Illinois, United States
Illinois CancerCare-Princeton
🇺🇸
Princeton, Illinois, United States
Franciscan Saint Anthony Health-Michigan City
🇺🇸
Michigan City, Indiana, United States
Siouxland Regional Cancer Center
🇺🇸
Sioux City, Iowa, United States
Cancer Center of Kansas-Manhattan
🇺🇸
Manhattan, Kansas, United States
University of Kansas Hospital-Westwood Cancer Center
🇺🇸
Westwood, Kansas, United States
Lafayette Family Cancer Center-EMMC
🇺🇸
Brewer, Maine, United States
Penobscot Bay Medical Center
🇺🇸
Rockport, Maine, United States
Beverly Hospital
🇺🇸
Beverly, Massachusetts, United States
IHA Hematology Oncology Consultants-Brighton
🇺🇸
Brighton, Michigan, United States
Addison Gilbert Hospital
🇺🇸
Gloucester, Massachusetts, United States
Saint Joseph Mercy Hospital
🇺🇸
Ann Arbor, Michigan, United States
Saint Joseph Mercy Canton
🇺🇸
Canton, Michigan, United States
Spectrum Health at Butterworth Campus
🇺🇸
Grand Rapids, Michigan, United States
Great Lakes Cancer Management Specialists-Doctors Park
🇺🇸
East China Township, Michigan, United States
Hurley Medical Center
🇺🇸
Flint, Michigan, United States
Lymphoma Clinic of Michigan
🇺🇸
Grosse Pointe Woods, Michigan, United States
Michigan Breast Specialists-Grosse Pointe Woods
🇺🇸
Grosse Pointe Woods, Michigan, United States
Lakeland Community Hospital
🇺🇸
Niles, Michigan, United States
Huron Medical Center PC
🇺🇸
Port Huron, Michigan, United States
UP Health System Hematology Oncology Marquette
🇺🇸
Marquette, Michigan, United States
Sparrow Hospital
🇺🇸
Lansing, Michigan, United States
UP Health System Marquette
🇺🇸
Marquette, Michigan, United States
21st Century Oncology-Pontiac
🇺🇸
Pontiac, Michigan, United States
Great Lakes Cancer Management Specialists-Rochester Hills
🇺🇸
Rochester Hills, Michigan, United States
Great Lakes Cancer Management Specialists-Macomb Professional Building
🇺🇸
Warren, Michigan, United States
Lakeland Hospital
🇺🇸
Saint Joseph, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC
🇺🇸
Saginaw, Michigan, United States
Saint John Macomb-Oakland Hospital
🇺🇸
Warren, Michigan, United States
Macomb Hematology Oncology PC
🇺🇸
Warren, Michigan, United States
Mercy Hospital
🇺🇸
Coon Rapids, Minnesota, United States
Huron Gastroenterology PC
🇺🇸
Ypsilanti, Michigan, United States
Metro Health Hospital
🇺🇸
Wyoming, Michigan, United States
Park Nicollet Clinic - Saint Louis Park
🇺🇸
Saint Louis Park, Minnesota, United States
North Memorial Medical Health Center
🇺🇸
Robbinsdale, Minnesota, United States
Baptist Memorial Hospital and Cancer Center-Union County
🇺🇸
New Albany, Mississippi, United States
Rice Memorial Hospital
🇺🇸
Willmar, Minnesota, United States
Baptist Memorial Hospital and Cancer Center-Oxford
🇺🇸
Oxford, Mississippi, United States
Saint Francis Medical Center
🇺🇸
Cape Girardeau, Missouri, United States
Singing River Hospital
🇺🇸
Pascagoula, Mississippi, United States
Mercy Hospital Saint Louis
🇺🇸
Saint Louis, Missouri, United States
Saint Louis Cancer and Breast Institute-South City
🇺🇸
Saint Louis, Missouri, United States
CHI Health Saint Francis
🇺🇸
Grand Island, Nebraska, United States
Nebraska Hematology and Oncology
🇺🇸
Lincoln, Nebraska, United States
Saint Elizabeth Regional Medical Center
🇺🇸
Lincoln, Nebraska, United States
Cancer and Blood Specialists-Henderson
🇺🇸
Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada-Horizon Ridge
🇺🇸
Henderson, Nevada, United States
21st Century Oncology
🇺🇸
Las Vegas, Nevada, United States
Regional West Medical Center Cancer Center
🇺🇸
Scottsbluff, Nebraska, United States
Ann M Wierman MD LTD
🇺🇸
Las Vegas, Nevada, United States
Nevada Cancer Specialists-Fort Apache
🇺🇸
Las Vegas, Nevada, United States
Radiation Oncology Associates
🇺🇸
Reno, Nevada, United States
Hope Cancer Care of Nevada-Pahrump
🇺🇸
Pahrump, Nevada, United States
Faxton-Saint Luke's Healthcare
🇺🇸
Utica, New York, United States
Englewood Hospital and Medical Center
🇺🇸
Englewood, New Jersey, United States
Newark Beth Israel Medical Center
🇺🇸
Newark, New Jersey, United States
Orange Regional Medical Center
🇺🇸
Middletown, New York, United States
Southeastern Medical Oncology Center-Jacksonville
🇺🇸
Jacksonville, North Carolina, United States
Roger Maris Cancer Center
🇺🇸
Fargo, North Dakota, United States
Sanford Bismarck Medical Center
🇺🇸
Bismarck, North Dakota, United States
Southeastern Medical Oncology Center-Wilson
🇺🇸
Wilson, North Carolina, United States
Indu and Raj Soin Medical Center
🇺🇸
Beavercreek, Ohio, United States
Adena Regional Medical Center
🇺🇸
Chillicothe, Ohio, United States
Oncology Hematology Care Inc-Mercy West
🇺🇸
Cincinnati, Ohio, United States
Good Samaritan Hospital - Cincinnati
🇺🇸
Cincinnati, Ohio, United States
Mount Carmel Health Center West
🇺🇸
Columbus, Ohio, United States
Delaware Health Center-Grady Cancer Center
🇺🇸
Delaware, Ohio, United States
Orion Cancer Care
🇺🇸
Findlay, Ohio, United States
Oncology Hematology Care Inc-Healthplex
🇺🇸
Fairfield, Ohio, United States
Kettering Medical Center
🇺🇸
Kettering, Ohio, United States
Saint Ann's Hospital
🇺🇸
Westerville, Ohio, United States
Upper Valley Medical Center
🇺🇸
Troy, Ohio, United States
Providence Medford Medical Center
🇺🇸
Medford, Oregon, United States
Ephrata Community Hospital
🇺🇸
Ephrata, Pennsylvania, United States
University of Oklahoma Health Sciences Center
🇺🇸
Oklahoma City, Oklahoma, United States
Lehigh Valley Hospital-Cedar Crest
🇺🇸
Allentown, Pennsylvania, United States
Cherry Tree Cancer Center
🇺🇸
Hanover, Pennsylvania, United States
Ephrata Cancer Center
🇺🇸
Ephrata, Pennsylvania, United States
UPMC-Presbyterian Hospital
🇺🇸
Pittsburgh, Pennsylvania, United States
UPMC-Saint Margaret
🇺🇸
Pittsburgh, Pennsylvania, United States
UPMC-Magee Womens Hospital
🇺🇸
Pittsburgh, Pennsylvania, United States
Penn State Health Saint Joseph Medical Center
🇺🇸
Reading, Pennsylvania, United States
UPMC Cancer Center at UPMC Northwest
🇺🇸
Seneca, Pennsylvania, United States
UPMC Washington Hospital Radiation Oncology
🇺🇸
Washington, Pennsylvania, United States
McLeod Regional Medical Center
🇺🇸
Florence, South Carolina, United States
Saint Francis Hospital
🇺🇸
Federal Way, Washington, United States
Greenville Memorial Hospital
🇺🇸
Greenville, South Carolina, United States
Greenville Health System Cancer Institute-Seneca
🇺🇸
Seneca, South Carolina, United States
Greenville Health System Cancer Institute-Eastside
🇺🇸
Greenville, South Carolina, United States
Memorial Hospital
🇺🇸
Chattanooga, Tennessee, United States
Saint Joseph Regional Cancer Center
🇺🇸
Bryan, Texas, United States
Norris Cotton Cancer Center-North
🇺🇸
Saint Johnsbury, Vermont, United States
Saint Mary's Medical Center
🇺🇸
Huntington, West Virginia, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo
🇺🇸
Poulsbo, Washington, United States
Gundersen Lutheran Medical Center
🇺🇸
La Crosse, Wisconsin, United States
Marshfield Clinic Cancer Center at Sacred Heart
🇺🇸
Eau Claire, Wisconsin, United States
Marshfield Clinic
🇺🇸
Marshfield, Wisconsin, United States
Marshfield Clinic - Ladysmith Center
🇺🇸
Ladysmith, Wisconsin, United States
Marshfield Clinic Stevens Point Center
🇺🇸
Stevens Point, Wisconsin, United States
Cancer Center of Western Wisconsin
🇺🇸
New Richmond, Wisconsin, United States
Vince Lombardi Cancer Clinic-Two Rivers
🇺🇸
Two Rivers, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh
🇺🇸
Oshkosh, Wisconsin, United States
Aurora Cancer Care-Waukesha
🇺🇸
Waukesha, Wisconsin, United States
Lakeview Medical Center-Marshfield Clinic
🇺🇸
Rice Lake, Wisconsin, United States
Aspirus Regional Cancer Center
🇺🇸
Wausau, Wisconsin, United States
Yale University
🇺🇸
New Haven, Connecticut, United States
Jewish Hospital
🇺🇸
Louisville, Kentucky, United States
Saints Mary and Elizabeth Hospital
🇺🇸
Louisville, Kentucky, United States
Jewish Hospital Medical Center Northeast
🇺🇸
Louisville, Kentucky, United States
Truman Medical Center
🇺🇸
Kansas City, Missouri, United States
Saint Luke's Hospital of Kansas City
🇺🇸
Kansas City, Missouri, United States
Heartland Hematology and Oncology Associates Incorporated
🇺🇸
Kansas City, Missouri, United States
Kansas City Veterans Affairs Medical Center
🇺🇸
Kansas City, Missouri, United States
The University of Kansas Cancer Center-South
🇺🇸
Kansas City, Missouri, United States
The University of Kansas Cancer Center-North
🇺🇸
Kansas City, Missouri, United States
Research Medical Center
🇺🇸
Kansas City, Missouri, United States
Hawaii Cancer Care Inc-POB II
🇺🇸
Honolulu, Hawaii, United States
Hawaii Oncology Inc-POB I
🇺🇸
Honolulu, Hawaii, United States
Island Urology
🇺🇸
Honolulu, Hawaii, United States
Queen's Medical Center
🇺🇸
Honolulu, Hawaii, United States
Straub Clinic and Hospital
🇺🇸
Honolulu, Hawaii, United States
University of Hawaii Cancer Center
🇺🇸
Honolulu, Hawaii, United States
Hawaii Cancer Care Inc-Liliha
🇺🇸
Honolulu, Hawaii, United States
Hawaii Oncology Inc-Kuakini
🇺🇸
Honolulu, Hawaii, United States
Kuakini Medical Center
🇺🇸
Honolulu, Hawaii, United States
The Cancer Center of Hawaii-Liliha
🇺🇸
Honolulu, Hawaii, United States
Kapiolani Medical Center for Women and Children
🇺🇸
Honolulu, Hawaii, United States
Medical Oncology and Hematology Associates-Laurel
🇺🇸
Des Moines, Iowa, United States
Mercy Medical Center - Des Moines
🇺🇸
Des Moines, Iowa, United States
Saint Joseph Radiation Oncology Resource Center
🇺🇸
Lexington, Kentucky, United States
Saint Joseph Hospital East
🇺🇸
Lexington, Kentucky, United States
Associates In Womens Health
🇺🇸
Wichita, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower
🇺🇸
Wichita, Kansas, United States
Cancer Center of Kansas - Wichita
🇺🇸
Wichita, Kansas, United States
Via Christi Regional Medical Center
🇺🇸
Wichita, Kansas, United States
Lovelace Medical Center-Saint Joseph Square
🇺🇸
Albuquerque, New Mexico, United States
University of New Mexico Cancer Center
🇺🇸
Albuquerque, New Mexico, United States
New Mexico Oncology Hematology Consultants
🇺🇸
Albuquerque, New Mexico, United States
University of Rochester
🇺🇸
Rochester, New York, United States
Good Samaritan Hospital - Dayton
🇺🇸
Dayton, Ohio, United States
Miami Valley Hospital
🇺🇸
Dayton, Ohio, United States
Dayton Physicians LLC-Samaritan North
🇺🇸
Dayton, Ohio, United States
Samaritan North Health Center
🇺🇸
Dayton, Ohio, United States
Missouri Baptist Sullivan Hospital
🇺🇸
Sullivan, Missouri, United States
Missouri Baptist Outpatient Center-Sunset Hills
🇺🇸
Sunset Hills, Missouri, United States
Aurora Cancer Care-Grafton
🇺🇸
Grafton, Wisconsin, United States
Memorial and Saint Elizabeth's Health Care Services LLP
🇺🇸
Swansea, Illinois, United States
Liberty Radiation Oncology Center
🇺🇸
Liberty, Missouri, United States
Sechler Family Cancer Center
🇺🇸
Lebanon, Pennsylvania, United States
UPMC Uniontown Hospital Radiation Oncology
🇺🇸
Uniontown, Pennsylvania, United States