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临床试验/NCT01663597
NCT01663597
已完成
不适用

Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes

Medical University of Vienna1 个研究点 分布在 1 个国家目标入组 160 人2012年8月

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Refractive Errors
发起方
Medical University of Vienna
入组人数
160
试验地点
1
主要终点
Axial eye length
状态
已完成
最后更新
12年前

概览

简要总结

Aberrations play a significant role in the visual process and can be divided in lower-order and higher-order aberrations. The former can be measured using the commercially available IOL Master (Carl Zeiss Meditec AG, Germany) and have profound influence on visual acuity. Higher-order aberrations do not significantly influence visual acuity but affect the quality of vision and can cause halos, double vision, and night vision disturbances.

Background Cataract surgery has become a routine procedure in the developed countries. During this surgery, a foldable intraocular lens is usually inserted into the capsular bag. However, these lenses do not account for individual optical biometry data or aberrations. Therefore, it is important to provide data for ametropic and emmetropic eyes as this information might improve future intraocular lens design and lead to individually adapted lenses for yielding optimal visual acuity and quality results.

The aim of the present study is to clarify the correlation between refractive errors/axial eye length and spherical aberrations of the cornea.

注册库
clinicaltrials.gov
开始日期
2012年8月
结束日期
2013年5月
最后更新
12年前
研究类型
Observational
性别
All

研究者

责任方
Principal Investigator
主要研究者

Gerhard Garhofer

Assoc. Prof. Priv. Doz. Dr.

Medical University of Vienna

入排标准

入选标准

  • men and women aged between 40 and 60 years
  • normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
  • normal ophthalmic findings unless the investigator considers an abnormality to be clinically irrelevant

排除标准

  • presence of any corneal or retinal disease
  • Dry eye syndrome
  • high astigmatism (\>1 diopter)
  • history of refractive surgery
  • abuse of alcoholic beverages
  • participation in a clinical trial in the 3 weeks preceding the study
  • symptoms of a clinically relevant illness in the 3 weeks before the study day
  • pregnancy

结局指标

主要结局

Axial eye length

时间窗: 1 day

次要结局

  • Refractive error(1 day)
  • Corneal radius(1 day)
  • Pupil diameter(1 day)
  • Anterior chamber depth(1 day)
  • Anterior corneal topography(1 day)
  • Corneal thickness map(1 day)

研究点 (1)

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