Optical Biometry and Spherical Aberration in Ametropic and Emmetropic Eyes
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- Refractive Errors
- 发起方
- Medical University of Vienna
- 入组人数
- 160
- 试验地点
- 1
- 主要终点
- Axial eye length
- 状态
- 已完成
- 最后更新
- 12年前
概览
简要总结
Aberrations play a significant role in the visual process and can be divided in lower-order and higher-order aberrations. The former can be measured using the commercially available IOL Master (Carl Zeiss Meditec AG, Germany) and have profound influence on visual acuity. Higher-order aberrations do not significantly influence visual acuity but affect the quality of vision and can cause halos, double vision, and night vision disturbances.
Background Cataract surgery has become a routine procedure in the developed countries. During this surgery, a foldable intraocular lens is usually inserted into the capsular bag. However, these lenses do not account for individual optical biometry data or aberrations. Therefore, it is important to provide data for ametropic and emmetropic eyes as this information might improve future intraocular lens design and lead to individually adapted lenses for yielding optimal visual acuity and quality results.
The aim of the present study is to clarify the correlation between refractive errors/axial eye length and spherical aberrations of the cornea.
研究者
Gerhard Garhofer
Assoc. Prof. Priv. Doz. Dr.
Medical University of Vienna
入排标准
入选标准
- •men and women aged between 40 and 60 years
- •normal findings in the medical history unless the investigator considers an abnormality to be clinically irrelevant
- •normal ophthalmic findings unless the investigator considers an abnormality to be clinically irrelevant
排除标准
- •presence of any corneal or retinal disease
- •Dry eye syndrome
- •high astigmatism (\>1 diopter)
- •history of refractive surgery
- •abuse of alcoholic beverages
- •participation in a clinical trial in the 3 weeks preceding the study
- •symptoms of a clinically relevant illness in the 3 weeks before the study day
- •pregnancy
结局指标
主要结局
Axial eye length
时间窗: 1 day
次要结局
- Refractive error(1 day)
- Corneal radius(1 day)
- Pupil diameter(1 day)
- Anterior chamber depth(1 day)
- Anterior corneal topography(1 day)
- Corneal thickness map(1 day)