Management of Psoriasis through panchakarma
- Conditions
- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere. Ayurveda Condition: KITIBAH,
- Registration Number
- CTRI/2021/10/037687
- Lead Sponsor
- All India Institute of Ayurveda
- Brief Summary
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Psoriasis is an immune-mediated inflammatory disorder characterized by marked inflammatory changes in the epidermis and dermis.it predominantly affects people in their third or fourth decades, with males two times higher than females.
In Ayurveda, all the skin disease is described under the broad term of “*Kushtha*â€. Psoriasis can be diagnosed as *Ekakushtha, Kitibha Kushtha, Sidhma Kushtha which* are considered as the *Kshudra Kushtha*. They are said to be *Tridoshaja* with the dominance of Vata-*Kapha Dosha*. The classical symptoms of *Kitibha Kushtha are*described in *Ayurveda* resembles with Psoriasis. Clinical features of Psoriasis *[Rupa of Kitibha Kushtha]* are Blackish skin lesions *(Shyava)*, Scarring of skin *(Kinna)*, Rough skin *(Kharasparsha)*, Dry cracked skin *(Parusha)*, Itching *(Kandu)*, Thickened skin *(Ghana).*Due to complex pathophysiology and chronic and relapsing nature of Psoriasis. Nowadays everyone interested in the dynamic interplay that leads to psoriasis,as well as gene products that may serve as a connection between predisposing genetic factors and the immune and inflammatory processes involved in the disease;s pathogenesis. Hence biomarkers could be relevant for,assessment of disease activity and severity and for prediction of the outcome of therapeutic intervention.
*Acharya Charaka* mentions repeated *Shodhana* in context of *Bahudosha Avastha Janya* *Vyadhi* “*Kushtha*. It deals mainly with elimination of aggravated *Doshas* from the body. These Doshas should be eliminated naturally through nearest route of the body.
There are various studies on the efficacy of *Shodhana Karma* in Psoriasis *(Kitibha Kushtha*). Such studies reported significant relief in sign and symptoms of psoriasis and better quality of life with no further episodes of recurrence after repeated *Shodhana karma* in regular interval of time.It is the need of hour to overview the role of immunological and inflammatory biomarkers that can help us to understand the role of ayurvedic management Shodhana karma and its influence on autoimmune biomarkers specific to psoriasis.
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- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
PASI Score: > 10 Moderate to severe Chronicity: up to10 years Patients having the clinical features of Psoriasis (Kitibha Kushtha).
Chronicity of more than 10 years PASI score <10 Patients with Severe Systemic disorders Pregnant women and lactating mothers Patients unfit for Rookshana Snehana, Swedana,Vamana and Virechana Karma.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2.Symptomatic Relief in signs and symptoms of Psoriasis 0th,23rd,40th,80th 1.Change in Immunological and inflammatory Biomarkers. 0th,23rd,40th,80th 3.Reduction in Psoriasis Area and Severity Index (PASI) Score. 0th,23rd,40th,80th
- Secondary Outcome Measures
Name Time Method Improvement in DLQI quality of life 0th,23rd,40th,80th
Trial Locations
- Locations (1)
All India Institute of Ayurveda
🇮🇳West, DELHI, India
All India Institute of Ayurveda🇮🇳West, DELHI, IndiaDr LatikaPrincipal investigator8860880119latikakundra92@gmail.com